| Type | Description |
|---|---|
| Definition | ring finger protein 128 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 10:56:00 | RNF128 downregulation was shown to correlate with the malignant phenotype of melanoma, and further functional assays demonstrated that low levels of RNF128 promoted melanoma progression via inducing cell epithelial-mesenchymal transition (EMT) and the acquisition of stemness. | 30832692 |
| 2020-04-11 12:41:00 | We found that isoform 2 of RNF128 is decreased in BE cells, resulting in increased levels of mutant p53, whereas isoform 1 of RNF128 is increased in BE cells, further promoting the stabilization of mutant p53. | 31715145 |
| 2019-11-02 10:54:00 | Results demonstrate that Grail acts as a negative regulator of influenza A virus infection and replication by degrading viral nucleoprotein. | 30467324 |
| 2015-10-24 10:42:00 | results show that expression of GRAIL is uniquely regulated by the specific miRNA in intestinal mucosa, and suggest that GRAIL may associate with the pathophysiology of Crohn's disease | 24356810 |
| 2013-10-19 14:36:00 | study shows that Grail has a novel, p53-dependent role in regulating the cell cycle and apoptosis | 23370271 |
| Type | IDs |
|---|---|
| Synonymous | GRAIL |
| Gene |
UniProtKB-ID:
RN128_HUMAN
UniprotKB:
Q8TEB7
UniParc:
UPI0000046A7A,
UPI00001C0CAA
EMBL:
AF394689,
AK126553,
AK074264,
AL606833,
BC030951,
AL391315,
BC056677,
BC063404,
AK027169
Ensembl:
ENSG00000133135
KO:
hsa:79589
|
| Nucleutide sequences |
EMBL-CDS:
AAH56677.1,
BAC86589.1,
AAH30951.1,
BAB15682.1,
AAK77554.1,
BAB85033.1,
AAH63404.1
Ensembl_TRS:
ENST00000324342,
ENST00000255499
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000316127,
ENSP00000255499
RefSeq:
NP_919445.1,
NP_078815.3
|
| Others |
UniRef100:
UniRef100_Q8TEB7
UniRef90:
UniRef90_Q8TEB7
UniRef50:
UniRef50_Q8TEB7
UniGene:
Hs.496542
CCDS:
CCDS14521.1,
CCDS14520.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员