| Type | Description |
|---|---|
| Definition | lipoic acid synthetase |
| Date | Results | Publications |
|---|---|---|
| 2012-11-17 10:47:00 | Decreased endogenous lipoic acid gene expression plays a role in development of diabetic atherosclerosis in ApoE deficient mice. | 22658261 |
| 2012-03-10 10:25:00 | deficiency increases oxidative stress and accelerates the development of diabetic nephropathy | 22021711 |
| 2010-12-11 10:54:00 | Lias deficiency enhances atherosclerosis in male mice, at least in part due to reduced antioxidant capacity | 20347443 |
| 2010-01-21 00:00:00 | Enhanced neutrophil sequestration in the livers of Lias+/- mice was associated with increased hepatocyte injury and increased gene expression of growth-related oncogene, E-selectin, and VCAM-1 in the liver and/or lung. | 18845616 |
| 2010-01-21 00:00:00 | Development of homozygous embryos lacking Lias is retarded. | 16135825 |
| Type | IDs |
|---|---|
| Synonymous | 2900022L22Rik, 4933425M12Rik, 7a5ex, C77512, LS, lip-syn |
| Gene |
UniProtKB-ID:
LIAS_MOUSE,
A0A0M3HEP3_MOUSE
UniprotKB:
Q99M04,
A0A0M3HEP3
UniParc:
UPI0001611821,
UPI0000004094
EMBL:
AC136513,
BC002141,
AK077192,
AK048744,
AK049548,
AB057731
Ensembl:
ENSMUSG00000029199
KO:
mmu:79464
|
| Nucleutide sequences |
EMBL-CDS:
BAC33443.1,
BAC33804.1,
AAH02141.1,
BAC36672.1,
BAB62009.1
Ensembl_TRS:
ENSMUST00000122026,
ENSMUST00000031101
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113228,
ENSMUSP00000031101
RefSeq:
NP_001297541.1,
NP_077791.1,
XP_030110773.1
|
| Others |
UniRef100:
UniRef100_Q99M04
UniRef90:
UniRef90_Q99M04
UniRef50:
UniRef50_Q99M04
UniGene:
Mm.195776
CCDS:
CCDS19307.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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