| Type | Description |
|---|---|
| Definition | grainyhead-like transcription factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2016-09-03 12:13:00 | We demonstrated that this variant impairs GRHL3 function and periderm development in zebrafish and is likely to be the etiologic variant for this cleft palate risk locus. | 27018472 |
| 2015-06-27 13:15:00 | Phylogenetic analysis of conserved grhl-binding sites in gene regulatory regions identified endothelin-1 (edn1) as a putative direct grhl3 target gene, and this was confirmed by chromatin precipitation assays in embryos. | 24915580 |
| 2013-04-06 13:05:00 | In zebrafish periderm, grainyhead-like 3 (grhl3) (an ancient regulator of the epidermal permeability barrier), was identified as acting downstream of Irf6. Simultaneous inhibition of grhl1 and grhl3 disrupted periderm differentiation in zebrafish. | 22931925 |
| Type | IDs |
|---|---|
| Synonymous | cb467, sb:cb467, si:dkey-221l4.7, wu:fa01c12, wu:fb74c01 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_021323103.1,
XP_021323102.1,
XP_005158615.2,
XP_021328861.1,
XP_021323104.1
|
| Others |
UniGene:
Dr.75375
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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