| Type | Description |
|---|---|
| Definition | FYVE and coiled-coil domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-04 11:52:00 | FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation | 29196475 |
| 2018-01-06 10:16:00 | FYCO1 and MAP1LC3A interact through a novel binding mode that involves Atg8-family proteins | 27246247 |
| 2017-07-01 10:54:00 | Rare missense variants in FYCO1 are overrepresented in sporadic inclusion body myositis patients. | 28009083 |
| 2016-04-23 10:55:00 | FYCO1 requires a functional LC3A/B-preferring LC3-interacting Region (LIR) motif to facilitate efficient maturation of autophagosomes under basal conditions, whereas starvation-induced autophagy was unaffected | 26468287 |
| 2011-08-20 10:49:00 | FYCO1 is involved in lens development and transparency in humans, and mutations in this gene are one of the most common causes of autosomal-recessive congenital cataracts in the Pakistani population. | 21636066 |
| Type | IDs |
|---|---|
| Synonymous | CATC2, CTRCT18, RUFY3, ZFYVE7 |
| Gene |
UniProtKB-ID:
FYCO1_HUMAN
UniprotKB:
Q9BQS8
UniParc:
UPI0001F4E01A,
UPI000013E307,
UPI000189A737,
UPI00004122EB
EMBL:
AK074165,
BC007218,
AL832358,
BC143368,
AJ292348,
BC101468,
AC099782,
BC101470,
AK023397,
AL833308
Ensembl:
ENSG00000163820
KO:
hsa:79443
|
| Nucleutide sequences |
EMBL-CDS:
AAI43369.1,
AAI01469.1,
CAD91151.1,
BAB84991.1,
BAB14559.1,
CAC33883.1,
AAH07218.1,
AAI01471.1,
CAD89924.1
Ensembl_TRS:
ENST00000535325,
ENST00000296137
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000441178,
ENSP00000296137
RefSeq:
NP_001373352.1,
NP_001373354.1,
NP_001373357.1,
NP_001373356.1,
NP_001373355.1,
NP_001373353.1,
NP_001373358.1,
NP_001373350.1,
NP_001373351.1,
XP_006713396.1,
NP_001373359.1,
NP_078789.2
|
| Others |
UniRef100:
UniRef100_Q9BQS8
UniRef90:
UniRef90_Q9BQS8
UniRef50:
UniRef50_Q9BQS8
UniGene:
Hs.200227,
Hs.739775
CCDS:
CCDS2734.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32838362 |
Med (N Y) Jingjiao Li , Mingquan Guo , Xiaoxu Tian , Xin Wang , Xing Yang , Ping Wu , Chengrong Liu , Zixuan Xiao , Yafei Qu , Yue Yin , Chunxia Wang , Yucai Zhang , Zhaoqin Zhu , Zhenshan Liu , Chao Peng , Tongyu Zhu , Qiming Liang |
2021-01-15 | - |
| 33060197 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science David E Gordon , Joseph Hiatt , Mehdi Bouhaddou , Veronica V Rezelj , Svenja Ulferts , Hannes Braberg , Alexander S Jureka , Kirsten Obernier , Jeffrey Z Guo , Jyoti Batra , Robyn M Kaake , Andrew R Weckstein , Tristan W Owens , Meghna Gupta , Sergei Pourmal , Erron W Titus , Merve Cakir , Margaret Soucheray , Michael McGregor , Zeynep Cakir , Gwendolyn Jang , Matthew J O'Meara , Tia A Tummino , Ziyang Zhang , Helene Foussard , Ajda Rojc , Yuan Zhou , Dmitry Kuchenov , Ruth Hüttenhain , Jiewei Xu , Manon Eckhardt , Danielle L Swaney , Jacqueline M Fabius , Manisha Ummadi , Beril Tutuncuoglu , Ujjwal Rathore , Maya Modak , Paige Haas , Kelsey M Haas , Zun Zar Chi Naing , Ernst H Pulido , Ying Shi , Inigo Barrio-Hernandez , Danish Memon , Eirini Petsalaki , Alistair Dunham , Miguel Correa Marrero , David Burke , Cassandra Koh , Thomas Vallet , Jesus A Silvas , Caleigh M Azumaya , Christian Billesbølle , Axel F Brilot , Melody G Campbell , Amy Diallo , Miles Sasha Dickinson , Devan Diwanji , Nadia Herrera , Nick Hoppe , Huong T Kratochvil , Yanxin Liu , Gregory E Merz , Michelle Moritz , Henry C Nguyen , Carlos Nowotny , Cristina Puchades , Alexandrea N Rizo , Ursula Schulze-Gahmen , Amber M Smith , Ming Sun , Iris D Young , Jianhua Zhao , Daniel Asarnow , Justin Biel , Alisa Bowen , Julian R Braxton , Jen Chen , Cynthia M Chio , Un Seng Chio , Ishan Deshpande , Loan Doan , Bryan Faust , Sebastian Flores , Mingliang Jin , Kate Kim , Victor L Lam , Fei Li , Junrui Li , Yen-Li Li , Yang Li , Xi Liu , Megan Lo , Kyle E Lopez , Arthur A Melo , Frank R Moss , Phuong Nguyen , Joana Paulino , Komal Ishwar Pawar , Jessica K Peters , Thomas H Pospiech , Maliheh Safari , Smriti Sangwan , Kaitlin Schaefer , Paul V Thomas , Aye C Thwin , Raphael Trenker , Eric Tse , Tsz Kin Martin Tsui , Feng Wang , Natalie Whitis , Zanlin Yu , Kaihua Zhang , Yang Zhang , Fengbo Zhou , Daniel Saltzberg , QCRG Structural Biology Consortium , Anthony J Hodder , Amber S Shun-Shion , Daniel M Williams , Kris M White , Romel Rosales , Thomas Kehrer , Lisa Miorin , Elena Moreno , Arvind H Patel , Suzannah Rihn , Mir M Khalid , Albert Vallejo-Gracia , Parinaz Fozouni , Camille R Simoneau , Theodore L Roth , David Wu , Mohd Anisul Karim , Maya Ghoussaini , Ian Dunham , Francesco Berardi , Sebastian Weigang , Maxime Chazal , Jisoo Park , James Logue , Marisa McGrath , Stuart Weston , Robert Haupt , C James Hastie , Matthew Elliott , Fiona Brown , Kerry A Burness , Elaine Reid , Mark Dorward , Clare Johnson , Stuart G Wilkinson , Anna Geyer , Daniel M Giesel , Carla Baillie , Samantha Raggett , Hannah Leech , Rachel Toth , Nicola Goodman , Kathleen C Keough , Abigail L Lind , Zoonomia Consortium , Reyna J Klesh , Kafi R Hemphill , Jared Carlson-Stevermer , Jennifer Oki , Kevin Holden , Travis Maures , Katherine S Pollard , Andrej Sali , David A Agard , Yifan Cheng , James S Fraser , Adam Frost , Natalia Jura , Tanja Kortemme , Aashish Manglik , Daniel R Southworth , Robert M Stroud , Dario R Alessi , Paul Davies , Matthew B Frieman , Trey Ideker , Carmen Abate , Nolwenn Jouvenet , Georg Kochs , Brian Shoichet , Melanie Ott , Massimo Palmarini , Kevan M Shokat , Adolfo GarcÃa-Sastre , Jeremy A Rassen , Robert Grosse , Oren S Rosenberg , Kliment A Verba , Christopher F Basler , Marco Vignuzzi , Andrew A Peden , Pedro Beltrao , Nevan J Krogan |
2020-12-04 | - |
| 32558485 |
Genomewide Association Study of Severe Covid-19 with Respiratory Failure. N Engl J Med Severe Covid-19 GWAS Group , David Ellinghaus , Frauke Degenhardt , Luis Bujanda , Maria Buti , AgustÃn Albillos , Pietro Invernizzi , Javier Fernández , Daniele Prati , Guido Baselli , Rosanna Asselta , Marit M Grimsrud , Chiara Milani , Fátima Aziz , Jan Kässens , Sandra May , Mareike Wendorff , Lars Wienbrandt , Florian Uellendahl-Werth , Tenghao Zheng , Xiaoli Yi , Raúl de Pablo , Adolfo G Chercoles , Adriana Palom , Alba-Estela Garcia-Fernandez , Francisco Rodriguez-Frias , Alberto Zanella , Alessandra Bandera , Alessandro Protti , Alessio Aghemo , Ana Lleo , Andrea Biondi , Andrea Caballero-Garralda , Andrea Gori , Anja Tanck , Anna Carreras Nolla , Anna Latiano , Anna Ludovica Fracanzani , Anna Peschuck , Antonio Julià , Antonio Pesenti , Antonio Voza , David Jiménez , Beatriz Mateos , Beatriz Nafria Jimenez , Carmen Quereda , Cinzia Paccapelo , Christoph Gassner , Claudio Angelini , Cristina Cea , Aurora Solier , David Pestaña , Eduardo Muñiz-Diaz , Elena Sandoval , Elvezia M Paraboschi , Enrique Navas , Félix GarcÃa Sánchez , Ferruccio Ceriotti , Filippo Martinelli-Boneschi , Flora Peyvandi , Francesco Blasi , Luis Téllez , Albert Blanco-Grau , Georg Hemmrich-Stanisak , Giacomo Grasselli , Giorgio Costantino , Giulia Cardamone , Giuseppe Foti , Serena Aneli , Hayato Kurihara , Hesham ElAbd , Ilaria My , Iván Galván-Femenia , Javier MartÃn , Jeanette Erdmann , Jose FerrusquÃa-Acosta , Koldo Garcia-Etxebarria , Laura Izquierdo-Sanchez , Laura R Bettini , Lauro Sumoy , Leonardo Terranova , Leticia Moreira , Luigi Santoro , Luigia Scudeller , Francisco Mesonero , Luisa Roade , Malte C Rühlemann , Marco Schaefer , Maria Carrabba , Mar Riveiro-Barciela , Maria E Figuera Basso , Maria G Valsecchi , MarÃa Hernandez-Tejero , Marialbert Acosta-Herrera , Mariella D'Angiò , Marina Baldini , Marina Cazzaniga , Martin Schulzky , Maurizio Cecconi , Michael Wittig , Michele Ciccarelli , Miguel RodrÃguez-GandÃa , Monica Bocciolone , Monica Miozzo , Nicola Montano , Nicole Braun , Nicoletta Sacchi , Nilda MartÃnez , Onur Ãzer , Orazio Palmieri , Paola Faverio , Paoletta Preatoni , Paolo Bonfanti , Paolo Omodei , Paolo Tentorio , Pedro Castro , Pedro M Rodrigues , Aaron Blandino Ortiz , Rafael de Cid , Ricard Ferrer , Roberta Gualtierotti , Rosa Nieto , Siegfried Goerg , Salvatore Badalamenti , Sara Marsal , Giuseppe Matullo , Serena Pelusi , Simonas Juzenas , Stefano Aliberti , Valter Monzani , Victor Moreno , Tanja Wesse , Tobias L Lenz , Tomas Pumarola , Valeria Rimoldi , Silvano Bosari , Wolfgang Albrecht , Wolfgang Peter , Manuel Romero-Gómez , Mauro D'Amato , Stefano Duga , Jesus M Banales , Johannes R Hov , Trine Folseraas , Luca Valenti , Andre Franke , Tom H Karlsen |
2020-10-15 | - |
| 32037591 |
J Comp Neurol Ivan Mestres , Maximilian Einsiedel , June Möller , Beatriz Cardoso de Toledo |
2020-09-01 | - |
| 32744243 |
Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases. Acta Crystallogr F Struct Biol Commun Shunya Sakurai , Toshiyuki Shimizu , Umeharu Ohto |
2020-08-01 | - |
| 32353859 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature David E Gordon , Gwendolyn M Jang , Mehdi Bouhaddou , Jiewei Xu , Kirsten Obernier , Kris M White , Matthew J O'Meara , Veronica V Rezelj , Jeffrey Z Guo , Danielle L Swaney , Tia A Tummino , Ruth Hüttenhain , Robyn M Kaake , Alicia L Richards , Beril Tutuncuoglu , Helene Foussard , Jyoti Batra , Kelsey Haas , Maya Modak , Minkyu Kim , Paige Haas , Benjamin J Polacco , Hannes Braberg , Jacqueline M Fabius , Manon Eckhardt , Margaret Soucheray , Melanie J Bennett , Merve Cakir , Michael J McGregor , Qiongyu Li , Bjoern Meyer , Ferdinand Roesch , Thomas Vallet , Alice Mac Kain , Lisa Miorin , Elena Moreno , Zun Zar Chi Naing , Yuan Zhou , Shiming Peng , Ying Shi , Ziyang Zhang , Wenqi Shen , Ilsa T Kirby , James E Melnyk , John S Chorba , Kevin Lou , Shizhong A Dai , Inigo Barrio-Hernandez , Danish Memon , Claudia Hernandez-Armenta , Jiankun Lyu , Christopher J P Mathy , Tina Perica , Kala Bharath Pilla , Sai J Ganesan , Daniel J Saltzberg , Ramachandran Rakesh , Xi Liu , Sara B Rosenthal , Lorenzo Calviello , Srivats Venkataramanan , Jose Liboy-Lugo , Yizhu Lin , Xi-Ping Huang , YongFeng Liu , Stephanie A Wankowicz , Markus Bohn , Maliheh Safari , Fatima S Ugur , Cassandra Koh , Nastaran Sadat Savar , Quang Dinh Tran , Djoshkun Shengjuler , Sabrina J Fletcher , Michael C O'Neal , Yiming Cai , Jason C J Chang , David J Broadhurst , Saker Klippsten , Phillip P Sharp , Nicole A Wenzell , Duygu Kuzuoglu-Ozturk , Hao-Yuan Wang , Raphael Trenker , Janet M Young , Devin A Cavero , Joseph Hiatt , Theodore L Roth , Ujjwal Rathore , Advait Subramanian , Julia Noack , Mathieu Hubert , Robert M Stroud , Alan D Frankel , Oren S Rosenberg , Kliment A Verba , David A Agard , Melanie Ott , Michael Emerman , Natalia Jura , Mark von Zastrow , Eric Verdin , Alan Ashworth , Olivier Schwartz , Christophe d'Enfert , Shaeri Mukherjee , Matt Jacobson , Harmit S Malik , Danica G Fujimori , Trey Ideker , Charles S Craik , Stephen N Floor , James S Fraser , John D Gross , Andrej Sali , Bryan L Roth , Davide Ruggero , Jack Taunton , Tanja Kortemme , Pedro Beltrao , Marco Vignuzzi , Adolfo GarcÃa-Sastre , Kevan M Shokat , Brian K Shoichet , Nevan J Krogan |
2020-07-01 | - |
| 32636717 |
The plasma peptides of sepsis. Thanusi Thavarajah , Claudia C Dos Santos , Arthur S Slutsky , John C Marshall , Pete Bowden , Alexander Romaschin , John G Marshall |
2020-01-01 | - |
| 32355443 |
Mutations in FYCO1 identified in families with congenital cataracts. Mol Vis Hira Iqbal , Shahid Y Khan , Lin Zhou , Bushra Irum , Muhammad Ali , Mariya R Ahmed , Mohsin Shahzad , Muhammad Hassaan Ali , Muhammad Asif Naeem , Sheikh Riazuddin , J Fielding Hejtmancik , S Amer Riazuddin |
2020-01-01 | - |
| 31006538 |
Intrinsically Disordered Protein TEX264 Mediates ER-phagy. Mol. Cell Haruka Chino , Tomohisa Hatta , Tohru Natsume , Noboru Mizushima |
2019-06-06 | - |
| 30575818 |
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis. Oncogene Katrin Tiemann , Carolina Garri , Sang Bok Lee , Paymaneh D Malihi , Mincheol Park , Ruth M Alvarez , Li Peng Yap , Parag Mallick , Jonathan E Katz , Mitchell E Gross , Kian Kani |
2019-04-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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