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79255 Atf4

79255

Atf4

activating transcription factor 4

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition activating transcription factor 4

研究结论

Date Results Publications
2021-01-09 13:28:00 Regulation of the cerebrovascular smooth muscle cell phenotype by mitochondrial oxidative injury and endoplasmic reticulum stress in simulated microgravity rats via the PERK-eIF2alpha-ATF4-CHOP pathway. 32304741
2020-09-05 13:53:00 PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes. 31787756
2020-03-14 12:17:00 This study demonstrated that ATF4 is able to alleviate cerebral ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation through parkin-dependent mitophagy activity. 31416289
2019-10-26 11:04:00 These findings reveal a critical role for ATF4 in regulating the modulation of neuronal excitability by metabotropic GABAB receptors 29875265
2018-06-16 11:23:00 Results find that ATF4 down-regulation in both hippocampal and cortical neuron cultures reduces protein and RNA levels of RhoGDIalpha. The study identified a new cellular pathway in which ATF4 regulates the expression of RhoGDIalpha that in turn affects Rho GTPase protein levels, and thereby, controls cellular functions as diverse as memory and cell motility. 27841340

名称对应

Type IDs
Gene
UniProtKB-ID: ATF4_RAT, B0BMW3_RAT
UniprotKB: Q9ES19, B0BMW3
UniParc: UPI00000E702E
EMBL: BC158588, AF252627
Ensembl: ENSRNOG00000017801
KO: rno:79255
Nucleutide sequences
EMBL-CDS: AAG31732.1, AAI58589.1
Ensembl_TRS: ENSRNOT00000065304
Protein sequencees
Ensembl_PRO: ENSRNOP00000060302
RefSeq: NP_077379.1
Others
UniRef100: UniRef100_Q9ES19
UniRef90: UniRef90_Q9ES19
UniRef50: UniRef50_Q06507
UniGene: Rn.2423

全选

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研究热度

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