Abca2 - ATP binding cassette subfamily A member 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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79248 Abca2

基因描述

Type	Description
Definition	ATP binding cassette subfamily A member 2

研究结论

Date	Results	Publications
2014-02-22 10:47:00	control of ABCA2 expression level may be a key locus of regulation for esterification of plasma membrane-derived cholesterol through modulation of sphingolipid metabolism.	24201375
2012-03-03 11:15:00	Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin maturation and intracellular localization.	22086926
2010-01-21 00:00:00	ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination.	12210128
2010-01-21 00:00:00	ABCA2 is a marker of neural progenitors and neuronal subsets in the adult rodent brain.	16539677
2010-01-21 00:00:00	ABCA2 protein is expressed predominantly in oligodendrocytes, and the expression of the protein is upregulated in the brain during maturation, especially between postnatal days 6 and 19.	12483687

名称对应

Type	IDs
Synonymous	Abc2
Gene	UniProtKB-ID: ABCA2_RAT UniprotKB: Q9ESR9 UniParc: UPI00000E762B EMBL: AB037937 KO: rno:79248
Nucleutide sequences	EMBL-CDS: BAB16596.1
Protein sequencees	RefSeq: NP_077372.1, XP_017447542.1, XP_017447541.1, XP_006233707.1
Others	UniRef100: UniRef100_Q9ESR9 UniRef90: UniRef90_Q9ESR9 UniRef50: UniRef50_Q9ESR9 UniGene: Rn.13115

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
26510981	The ATP-Binding Cassette Transporter-2 (ABCA2) Overexpression Modulates Sphingosine Levels and Transcription of the Amyloid Precursor Protein (APP) Gene. Curr Alzheimer Res Warren Davis	2015-01-01	-
24201375	The ATP-binding cassette transporter-2 (ABCA2) regulates esterification of plasma membrane cholesterol by modulation of sphingolipid metabolism. Biochim. Biophys. Acta Warren Davis	2014-01-01	-
22871113	Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. J. Proteome Res. Chan Hyun Na , Drew R Jones , Yanling Yang , Xusheng Wang , Yanji Xu , Junmin Peng	2012-09-07	Rab1b, Tmem59, Msh6, LOC100360426, Sncb, Csnk1a1, Magi2, Cxcl2, Dnm1l, Gng3, Hcn2, Clasp2, Ubqln1, Gne, Stx1a, Txn1, Sec14l2, Gripap1, Mprip, Slc6a9, Ralb, Ap2m1, Nrxn2, Slc17a7, Vcp, Cap2, Dlgap2, Lmnb1, Trim28, Epb41l3, Ube2n, Gp1bb, Nup155, Bin1, Rpl6, H3f3b, Nlgn2, Prdx1, Psmc4, Psmc1, Epn1, Ppp2r1a, Hnrnpk, Lrrc7, Txnip, Uba3, Sv2b, Tpm3, Sv2a, Atp6v1b2, Rps20, Slc8a2, Rps3, Faf1, Ap2b1, Dnm1, Cacng8, Cdk5, Txnl1, Ggt7, Prkcd, Palm, Atp2c1, Dynlrb1, Kcnh7, Xpnpep1, Atxn10, Kcnq2, Cry2, Rab3c, Ndrg2, Camk2g, Pabpc1, Eef1a1, Slc12a5, Acsbg1, Tmem176b, Nme1, Tecr, Syngap1, Hip1, Gpm6b, Ehd4, Rasgrf1, Plpp3, Stip1, Caly, Aldoa, Aldoc, Atp1a1, Atp1a2, Atp1a3, Atp2b2, Cacna1c, Calm1, Camk2d, Ckb, Eno1, Gapdh
22086926	Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-Î² production by altering Nicastrin maturation and intracellular localization. J Biol Chem Vasiliki Michaki , Francesc X Guix , Krist'l Vennekens , Sebastian Munck , Colin Dingwall , John B Davis , Danyelle M Townsend , Kenneth D Tew , Fabian Feiguin , Bart De Strooper , Carlos G Dotti , Tina Wahle	2012-01-06	-
21810484	The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells. Biochim. Biophys. Acta Warren Davis	2011-12-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20704561	The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and AÎ² fragment generation. Curr Alzheimer Res W Davis	2010-11-01	-
19946888	Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins	2010-01-01	MED6, PDCD6IP, MED16, PIGK, DNAJB6, FARSB, DNM1L, ABCF2, HUWE1, ARPC3, ACTR3, ACTR2, RAD50, PREB, ACTR1B, LRPPRC, TRAP1, BCAP31, PLXNC1, LPCAT3, TNK2, PSME3, MPHOSPH9, FLOT1, DDX39A, AK6, ADAM10, PLIN3, CALCOCO2, CDK9, ABCC4, ZMPSTE24, AKAP8, BET1, MARCH6, KATNB1, ADAR, EMC8, BTN3A3, ATP8A1, NDC80, CDIPT, PGRMC2, TUBGCP3, ECI2, COG5, SLC25A17, LRRC41, SYNCRIP, MYBBP1A, DDX17, CHERP, HYOU1, IPO7, NOP56, ARL6IP5, HTATIP2, AGPAT1, ARFGEF2, RABAC1, SLU7, PRPF8, PAICS, CENPE, PMVK, KHDRBS1, CELF1, GNA13, CFL1, MGEA5, YME1L1, STAG2, CTSC, GIPC1, HBS1L, TUBGCP2, PGRMC1, MAN1A2, PNPLA6, MAGED2, ADCY3, EHD1, TOMM34, ERP29, YWHAQ, ASCC3, GCN1, IMMT, ILVBL, SLC27A4, SLC27A3, KIF2C, GLIPR1, CPSF6, DDX52, WWP2, CNTRL, CHD4, KRR1
17060448	"Skittish" Abca2 knockout mice display tremor, hyperactivity, and abnormal myelin ultrastructure in the central nervous system. Mol. Cell. Biol. Jody T Mack , Vladimir Beljanski , Athena M Soulika , Danyelle M Townsend , Carol B Brown , Warren Davis , Kenneth D Tew	2007-01-01	-
16539677	ABCA2 is a marker of neural progenitors and neuronal subsets in the adult rodent brain. J. Neurochem. Cyril Broccardo , Vincent Nieoullon , Rada Amin , FrÃ©dÃ©rique Masmejean , Sonia Carta , Sara Tassi , Matthieu Pophillat , Anna Rubartelli , Michel Pierres , GeneviÃ¨ve Rougon , AndrÃ© Nieoullon , GenÃ¨vieve Chazal , Giovanna Chimini	2006-04-01	-

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