| Type | Description |
|---|---|
| Definition | heat shock transcription factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:12:00 | Decreased expression of FBXW7 by ERK1/2 activation in drug-resistant cancer cells confers transcriptional activation of MDR1 by suppression of ubiquitin degradation of HSF1. | 32457290 |
| 2020-05-09 13:40:00 | localized to both the cytoplasm and nuclei of myometrial cells in both muscle layers throughout gestation | 31522994 |
| 2019-11-02 10:54:00 | Results identified a large number of novel HSF1 targets a majority of which are not heat shock proteins. It remains to be determined which of them contribute to the novel non-chaperone-dependent mechanism by which HSF1 protects neurons. Based on the HSF1-AB mutant, HSF1 was found to be able to protect neurons without trimerization but this is likely mediated through a non-transcriptional mechanism. | 30467350 |
| 2019-03-09 10:49:00 | Heat shock promotes inclusion body formation of mutant Htt and alleviates mutant Htt-induced HSF1 dysfunction. | 30143534 |
| 2018-08-04 10:47:00 | These findings indicated that heat stress stimulation in IEC6 cells induced the proapoptotic role of NFkappaB by regulating HSF1 and cJun activation. | 29257252 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
F1MAF1_RAT
UniprotKB:
F1MAF1
UniParc:
UPI00002511C9
EMBL:
AC139605
Ensembl:
ENSRNOG00000021732
KO:
rno:79245
|
| Nucleutide sequences |
Ensembl_TRS:
ENSRNOT00000050108
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000047030
RefSeq:
XP_006241952.1,
NP_077369.1,
XP_006241951.1,
XP_006241950.1,
XP_006241953.1
|
| Others |
UniRef100:
UniRef100_F1MAF1
UniRef90:
UniRef90_P38532
UniRef50:
UniRef50_Q00613
UniGene:
Rn.20418
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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