| Type | Description |
|---|---|
| Definition | lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 12:59:00 | Rod a-wave and cone b-wave amplitudes of electroretinograms were increased in Cntf (-/-) mice, but rod b-wave amplitudes were unchanged compared with those in WT mice. Up-regulated RPE65 and LRAT levels accelerated both the visual cycle rate and recovery rate of rod light sensitivity in Cntf (-/-) mice. | 30115683 |
| 2016-04-23 12:04:00 | examined LRAT regulatory region is sufficient to achieve strong and selective expression in the eye and testes but not in liver and other organs | 25317684 |
| 2016-01-30 11:31:00 | LRAT overexpression diminishes intracellular levels of biologically active retinoids and reduces retinoid antitumor efficacy in the murine melanoma | 25721651 |
| 2014-07-26 10:33:00 | Mislocalized M-opsin was degraded whereas mislocalized S-opsin accumulated in Lrat(-/-) cones before the onset of massive ventral/central cone degeneration. | 24664772 |
| 2012-09-29 10:45:00 | Studies provide mechanistic insights into how vitamin A is distributed to peripheral tissues in a regulated manner and identify LRAT as a critical component of this process. | 22637576 |
| Type | IDs |
|---|---|
| Synonymous | 1300010A18Rik, AI449251 |
| Gene |
UniProtKB-ID:
LRAT_MOUSE,
B2RUR5_MOUSE
UniprotKB:
Q9JI60,
B2RUR5
UniParc:
UPI0000022D78
EMBL:
BC141378,
BC141375,
AF255061,
AK004953
Ensembl:
ENSMUSG00000028003
KO:
mmu:79235
|
| Nucleutide sequences |
EMBL-CDS:
BAB23696.1,
AAF97787.1,
AAI41379.1,
AAI41376.1
Ensembl_TRS:
ENSMUST00000029632
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029632
RefSeq:
NP_076113.1
|
| Others |
UniRef100:
UniRef100_Q9JI60
UniRef90:
UniRef90_Q9JI60
UniRef50:
UniRef50_O95237
UniGene:
Mm.33921
CCDS:
CCDS17430.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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