| Type | Description |
|---|---|
| Definition | gap junction protein, alpha 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 10:51:00 | In agreement with the model and suggesting a conformational change that narrows the pore, Ca(2+) inhibits the water flux through Cx hemichannels. We conclude that Ca(2+) and voltage act allosterically to stabilize the closed conformation of Cx46 hemichannels. | 29158540 |
| 2017-05-13 22:04:00 | the role of the charged residues at the end of TM-1 in voltage sensing in Cx26, Cx46, and Cx50. | 27143357 |
| 2013-05-25 11:37:00 | These results suggest that the C-terminal region of rCx46 up to A311 (rCx46(35.3)) is necessary for its correct compartmentalization and internalization in the form of annular junctions | 23065326 |
| 2011-09-10 12:09:00 | Cx43 and Cx46 have novel functions in regulating each other's expression and turnover in a reciprocal manner in addition to their conventional roles as gap junction proteins in lens cells. | 21606502 |
| 2011-06-18 11:11:00 | Data provide evidence that the activation and inhibition of affect the rCx46-mediated membrane conductance as well as the voltage-dependent current inactivation in an inverse manner. | 9683738 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CXA3_RAT,
G3V747_RAT
UniprotKB:
P29414,
G3V747
UniParc:
UPI000019BAC3,
UPI0000052BE0
EMBL:
CH474049,
X57970,
AABR07018050,
LT990402
Ensembl:
ENSRNOG00000008847
KO:
rno:79217
|
| Nucleutide sequences |
EMBL-CDS:
CAA41036.1,
VZP20202.1,
EDM14337.1
Gene_ORFName:
rCG_23448
Ensembl_TRS:
ENSRNOT00000011699
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000011699
RefSeq:
NP_077352.1,
XP_008768999.1
|
| Others |
UniRef100:
UniRef100_G3V747,
UniRef100_P29414
UniRef90:
UniRef90_P29414
UniRef50:
UniRef50_P29414
UniGene:
Rn.10345
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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