| Type | Description |
|---|---|
| Definition | iroquois homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:11:00 | Downregulated microRNA-150 upregulates IRX1 to depress proliferation, migration, and invasion, but boost apoptosis of gastric cancer cells. | 31846199 |
| 2021-02-02 13:24:00 | Prognostic value of Iroquois homeobox 1 methylation in non-small cell lung cancers. | 32200543 |
| 2020-09-19 16:26:00 | IRX1 hypermethylation promotes heart failure by inhibiting CXCL14 expression. | 31640472 |
| 2020-01-18 11:39:00 | The variant rs12517904 of the IRX1 gene is functionally associated with the development of adolescent idiopathic scoliosis in the Chinese population. For rs12517904, patients were found to have a significantly higher frequency of allele T than the controls. For rs117273909, neither the genotype nor the allele frequency was significantly different between the patients and controls. | 30862593 |
| 2019-02-23 11:58:00 | Through a combination of sequencing studies on eighteen North Carolina macular dystrophy families, two novel overlapping duplications at the MCDR3 locus, in a gene desert downstream of IRX1 and upstream of ADAMTS16, have been reported. | 28790370 |
| Type | IDs |
|---|---|
| Synonymous | IRX-5, IRXA1 |
| Gene |
UniProtKB-ID:
IRX1_HUMAN
UniprotKB:
P78414
UniParc:
UPI00001B6455
EMBL:
AY335938,
BC029160,
AY335947,
U90307
Ensembl:
ENSG00000170549
KO:
hsa:79192
|
| Nucleutide sequences |
EMBL-CDS:
AAH29160.1,
AAB50005.1,
AAQ16544.1,
AAQ16553.1
Ensembl_TRS:
ENST00000302006
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000305244
RefSeq:
NP_077313.3,
XP_016865334.1
|
| Others |
UniRef100:
UniRef100_P78414
UniRef90:
UniRef90_P78414
UniRef50:
UniRef50_P78414
UniGene:
Hs.424156
CCDS:
CCDS34132.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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