| Type | Description |
|---|---|
| Definition | cysteine rich with EGF like domains 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:07:00 | ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism. | 32451439 |
| 2015-01-17 11:53:00 | intravesicular acidification by V-ATPase regulates the secretion of CRELD2 without relying on the balance of intracellular calcium ions and the expression of endoplasmic reticulum chaperones such as GRP78 and protein disulfide isomerase. | 24687431 |
| 2014-07-12 11:09:00 | We demonstrate that Armet and Creld2 are genotype-specific ER stress response proteins with substrate specificities, and that aggregation of mutant matrilin-3 is a key disease trigger in MED that could be exploited as a potential therapeutic target | 23956175 |
| 2014-05-17 10:29:00 | results strongly suggest that Creld2 may be directly regulated by BMP9 and ER stress response may play an important role in regulating osteogenic differentiation | 24019898 |
| 2010-01-21 00:00:00 | Mapping of CRELD2 by FISH shows that it maps to 22q13 rather than the GenBank reported locus of 22p13. | 16919896 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CREL2_HUMAN
UniprotKB:
Q6UXH1
UniParc:
UPI0000E56EE9,
UPI000052D557,
UPI000006E092,
UPI0000E56EEA,
UPI0000037217,
UPI0000E56EE8
EMBL:
AY358355,
DQ470676,
DQ470679,
DQ470677,
BC050675,
DQ470678,
CH471138,
AL671710,
AJ968414,
BC002894,
DQ470680
Ensembl:
ENSG00000184164
KO:
hsa:79174
|
| Nucleutide sequences |
EMBL-CDS:
ABF06671.1,
ABF06672.1,
AAQ88721.1,
AAH50675.1,
EAW73484.1,
EAW73483.1,
CAI91316.1,
ABF06669.1,
ABF06670.1,
AAH02894.1,
ABF06668.1
Gene_ORFName:
UNQ185/PRO211
Ensembl_TRS:
ENST00000407217,
ENST00000403427,
ENST00000328268,
ENST00000404488
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386034,
ENSP00000332223,
ENSP00000383938,
ENSP00000384111
RefSeq:
NP_001128573.1,
NP_001271246.1,
XP_005261794.1,
XP_011528674.1,
XP_005261795.1,
NP_001271247.1,
NP_077300.3,
XP_016884427.1
|
| Others |
UniRef100:
UniRef100_Q6UXH1
UniRef90:
UniRef90_Q6UXH1
UniRef50:
UniRef50_Q6UXH1
UniGene:
Hs.211282
CCDS:
CCDS63515.1,
CCDS14082.1,
CCDS46730.1,
CCDS63516.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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