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79159 NOL12

79159

NOL12

nucleolar protein 12

protein-coding

Homo sapiens

基因描述

Type Description
Definition nucleolar protein 12

研究结论

Date Results Publications
2020-02-08 11:53:00 Results show that NOL12 is important for nucleolar homeostasis, regulating its structure and the nucleolar levels of the multifunctional fibrillarin and nucleolin proteins. Moreover, NOL12 depletion to induce strong p53 activation leading to cell senescence suggesting an important role for NOL12 in replicative and chronological aging and its potential as aging biomarker. 30988155
2017-12-30 12:34:00 Nol12 is an RNA binding protein required for both ribosome maturation and genome integrity 29069457
2010-09-15 22:06:00 Observational study of gene-disease association. (HuGE Navigator) 19913121

名称对应

Type IDs
Synonymous Nop25, dJ37E16.7
Gene
UniProtKB-ID: NOL12_HUMAN, A0A024R1M6_HUMAN
UniprotKB: Q9UGY1, A0A024R1M6
UniParc: UPI0000073B12
EMBL: BC002808, AL160132, CR456463, CH471095, Z83844
Ensembl: ENSG00000273899
KO: hsa:79159
Nucleutide sequences
EMBL-CDS: CAG30349.1, AAH02808.1, CAB77148.1, EAW60180.1, EAW60179.1
Gene_ORFName: hCG_41849
Ensembl_TRS: ENST00000438329, ENST00000359114, ENST00000611699
Protein sequencees
Ensembl_PRO: ENSP00000482349, ENSP00000352021, ENSP00000403059
RefSeq: NP_077289.1
Others
UniRef100: UniRef100_Q9UGY1
UniRef90: UniRef90_Q9UGY1
UniRef50: UniRef50_Q9UGY1
UniGene: Hs.632778
CCDS: CCDS13955.1

全选

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研究热度

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