| Type | Description |
|---|---|
| Definition | TNFAIP3 interacting protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 10:16:00 | The increased inflammation of Map3k8(-/-) mice in allergic airway inflammation and colitis results from reduced ABIN-2 signaling, rather than blocked TPL-2 signaling. | 31401161 |
| 2019-08-03 10:07:00 | the data indicated that TNIP2 is significantly decreased in MODS following severe trauma, and it plays a protective role in MODS development by inhibiting the inflammation response and oxidative stress by preventing NFkappaB activation. | 30720079 |
| 2017-11-25 12:38:00 | RelAp43 interacts with the p105-ABIN2-TPL2 complex and we observe a strong perturbation of this complex in presence of M protein. | 29084252 |
| 2017-10-21 10:33:00 | Study reports the crystal structure of hABIN2 in complex with linear triubiquitin, which shows the ubiquitins with M1-linkage could form a right-handed helical trimer when bridging two hABIN2 dimers, and thus allow the assembly of a higher-order signaling complex with A20. | 27916521 |
| 2017-06-27 12:47:00 | Findings suggest an expanded role for the NF-kappaB network hub protein TNIP2 and reveals an association between TNIP2 and YLPM1, TNIP2 and ESCRT-I, together with many RNA processing proteins and a distinct set of mRNAs. | 27609421 |
| Type | IDs |
|---|---|
| Synonymous | ABIN2, FLIP1, KLIP |
| Gene |
UniProtKB-ID:
TNIP2_HUMAN,
D6RGJ2_HUMAN
UniprotKB:
Q8NFZ5,
D6RGJ2
UniParc:
UPI0000D4E461,
UPI00000702D2,
UPI000013FAD2
EMBL:
AL110117,
AL121750,
AK096296,
BC002740,
AJ304866,
AK026176,
AF372839,
CH471131
Ensembl:
ENSG00000168884
KO:
hsa:79155
|
| Nucleutide sequences |
EMBL-CDS:
EAW82516.1,
AAM21315.1,
BAG53250.1,
AAH02740.2,
EAW82514.1,
CAM28233.1,
BAB15382.1,
CAC34835.1
Ensembl_TRS:
ENST00000510267,
ENST00000315423,
ENST00000503235
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000427613,
ENSP00000321203,
ENSP00000426314
RefSeq:
NP_001154999.1,
NP_001278945.1,
NP_077285.3
|
| Others |
UniRef100:
UniRef100_Q8NFZ5,
UniRef100_D6RGJ2
UniRef90:
UniRef90_Q8NFZ5
UniRef50:
UniRef50_Q8NFZ5
UniGene:
Hs.368551
CCDS:
CCDS3362.1,
CCDS54714.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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