| Type | Description |
|---|---|
| Definition | Hoxa distal transcript antisense RNA |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 12:49:00 | Further study revealed that HOTTIP increased SRF expression as a competing endogenous RNA for miR-150, thus prompting hepatic stellate cells (HSCs) activation. Taken together, we provide a novel HOTTIP-miR-150-SRF signalling cascade in liver fibrosis. | 30548190 |
| 2020-04-25 10:59:00 | Results indicate the role long noncoding RNAs (lncRNAs)-HOTTIP play in the UV response in spermatogenic cells. | 31697875 |
| 2019-11-30 12:58:00 | The HOTTIP overexpression attenuated OGD-induced neuronal injury and imbalanced glycolytic metabolism by sponging miR-143, resulting in the de-repression of its endogenous target HK-2. Taken together, these findings improve understanding of the pathogenesis of ischemic stroke. | 30129112 |
| 2019-11-09 12:30:00 | Downregulation of HOTTIP also inhibited cell proliferation and reduced expressions of CyclinDl, CyclinD2, CyclinE1 and CyclinE2. Moreover, islet beta cells were arrested in G0/G1 phase after HOTTIP knockdown. | 30070332 |
| 2019-02-02 10:53:00 | HOTTIP is involved in the progression of liver fibrosis by promoting Hepatic Stellate Cell activation. The high level of HOTTIP downregulates miR-148a, thus to increase the level of TGFBR1 and TGFBR2 and contribute to liver fibrosis. | 30562760 |
| Type | IDs |
|---|---|
| Synonymous | Gm15053 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees | |
| Others |
UniGene:
Mm.97466
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员