| Type | Description |
|---|---|
| Definition | von Hippel-Lindau tumor suppressor |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 10:41:00 | vhl is required to maintain pronephric tubule and glomerulus integrity during zebrafish development, and suggests a role for VHL in endocytic vesicle trafficking | 29342457 |
| 2017-12-09 10:10:00 | the vhl(-/-) zebrafish kidney is characterized by an increased tubule diameter, disorganized cilia, the dramatic formation of cytoplasmic lipid vesicles, glycogen accumulation, aberrant cell proliferation and abnormal apoptosis. | 27491085 |
| 2017-08-19 12:24:00 | In this review, we have tried to bring together knowledge on the HIF/hypoxic signaling pathway in zebrafish, including what is known on VHL functions. | 28129856 |
| 2017-05-27 10:52:00 | by modulating hypoxia-inducible factor activity via up-regulation of VHL, FOXO3a (foxo3b) plays an important role in survival in response to hypoxic stress. | 27777301 |
| 2016-09-03 12:05:00 | Zebrafish embryos lacking endogenous vhl lead to defective phenotypes in the renal system that were characterized by the curved and cystic pronephric tubule or/and a cystic and malformed glomerulus. | 26194803 |
| Type | IDs |
|---|---|
| Synonymous | zgc:158722 |
| Gene |
UniProtKB-ID:
A1L296_DANRE
UniprotKB:
A1L296
UniParc:
UPI0000ECF0DF
EMBL:
BC129410
KO:
dre:791202
|
| Nucleutide sequences |
EMBL-CDS:
AAI29411.1
|
| Protein sequencees |
RefSeq:
NP_001074153.1
|
| Others |
UniRef100:
UniRef100_A1L296
UniRef90:
UniRef90_A1L296
UniRef50:
UniRef50_A1L296
UniGene:
Dr.90467
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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