| Type | Description |
|---|---|
| Definition | apurinic/apyrimidinic endodeoxyribonuclease 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 11:02:00 | Our findings provide an insight into the PTEN and APE1 overexpression protects against cardiac hypoxia/reoxygenation injury, which may be through inducing the PINK1/Parkin-mediated mitophagy. | 31432320 |
| 2019-02-23 12:18:00 | Changes in APE1 expression and sub-cellular distribution are implicated in inflammatory pain mechanisms mediated by APE1 redox functions. | 29772245 |
| 2018-06-30 10:21:00 | Study shows that genetically enhancing apurinic/apyrimidinic endonuclease expression or treatment with the small molecule, E3330, increases DNA repair. | 28965839 |
| 2018-05-26 12:00:00 | Our findings provided valuable insights into the redox function of APE1/Ref-1 in preventing Pi-induced VSMC calcification by inhibiting oxidative stress and osteoblastic differentiation, resulting in prevention of altered osteoblastic phenotypes in VSMCs. | 28946662 |
| 2018-01-13 12:59:00 | The results of this study suggest that Ape1 protects against neuron death by activating the ERK1/2 signaling pathway. | 27893608 |
| Type | IDs |
|---|---|
| Synonymous | APE, Apex, REF-1 |
| Gene |
UniProtKB-ID:
APEX1_RAT
UniprotKB:
P43138
UniParc:
UPI00000009BF
EMBL:
L27076,
BC078816,
AB023065,
D44495,
AF309114
Ensembl:
ENSRNOG00000009663
KO:
rno:79116
|
| Nucleutide sequences |
EMBL-CDS:
AAG40859.1,
BAA07938.1,
BAA82124.1,
AAA21019.1,
AAH78816.1
Ensembl_TRS:
ENSRNOT00000013176,
ENSRNOT00000087958
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000013176,
ENSRNOP00000068673
RefSeq:
NP_077062.1,
XP_017455294.1,
XP_006251975.1
|
| Others |
UniRef100:
UniRef100_P43138
UniRef90:
UniRef90_P27695
UniRef50:
UniRef50_P27695
UniGene:
Rn.5949
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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