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79114 Fgfr1

79114

Fgfr1

Fibroblast growth factor receptor 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition Fibroblast growth factor receptor 1

研究结论

Date Results Publications
2018-04-28 11:18:00 Suboptimal FGFR activation by a weak FGF1-FGFR dimer is sufficient to evoke a metabolic response, whereas full FGFR activation by stable and sustained dimerization is required to elicit a mitogenic response. 28813681
2017-10-21 10:22:00 To detect FGFR phosphorylation (pFGFR) levels and M1R-FGFR1 heteroreceptor complexes. 27815219
2017-10-14 12:59:00 In summary, high FGF23 levels increase FGFR1, whereas phosphaturia decreases Klotho expression through the activation of Wnt/beta-catenin pathway. 28515153
2017-01-28 11:53:00 It plays an important role as a key trigger of Intramuscular adipose tissue formation in vivo. 26154243
2016-09-17 11:43:00 FGFR-1 inhibition with PD173074 ameliorated pulmonary arterial hypertension and vascular remodeling, and rescued BMPR-II expression. 26535780

名称对应

Type IDs
Gene
UniProtKB-ID: FGFR1_RAT, Q63827_RAT
UniprotKB: Q04589, Q63827
UniParc: UPI000012A727, UPI00000E59E7
EMBL: AABR07026305, S54008, D12498, AABR07026306
Ensembl: ENSRNOG00000016050
KO: rno:79114
Nucleutide sequences
EMBL-CDS: BAA02059.1, AAB54274.1
Ensembl_TRS: ENSRNOT00000050980
Protein sequencees
Ensembl_PRO: ENSRNOP00000043459
RefSeq: XP_017455744.1, XP_006253385.1, XP_006253386.1, NP_077060.1, XP_017455742.1, XP_017455741.1, XP_017455740.1, XP_006253388.1, XP_006253389.1, XP_017455743.1
Others
UniRef100: UniRef100_Q04589, UniRef100_Q63827
UniRef90: UniRef90_Q63827, UniRef90_P16092
UniRef50: UniRef50_P11362
UniGene: Rn.9797, Rn.207203

全选

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研究热度

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