Mepe - matrix extracellular phosphoglycoprotein-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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79110 Mepe

基因描述

Type	Description
Definition	matrix extracellular phosphoglycoprotein

研究结论

Date	Results	Publications
2017-08-12 12:37:00	Four genes are expressed significantly higher in basal bone than in alveolar bone: SOST, E-11, DMP-1, and MEPE. Three of the proteins (SOST, MEPE, and DMP-1) are associated with mature osteocytes, indicating that basal bone has more mature osteocyte phenotypes because the immature osteocyte converts to a mature osteocyte as a result of bone mineralization.	27039006
2014-09-06 10:48:00	expression of matrix extracellular phosphoglycoprotein (MEPE) in cortical bone of the rat tibia after mechanical loading	24255709
2010-01-21 00:00:00	MEPE expression is bone cell-specific and induced by the BMP-2 signaling pathway	19617624
2010-01-21 00:00:00	MEPE is a candidate phosphatonin involved in phosphate homeostasis, acting in both the kidney and the gastrointestinal tract	19005008

名称对应

Type	IDs
Synonymous	OF45
Gene	UniProtKB-ID: MEPE_RAT, A0A4X0WLY2_RAT UniprotKB: Q9ES02, A0A4X0WLY2 UniParc: UPI0000199F8D, UPI00000E5908, UPI00000E75B5 EMBL: AF530559, AF260922, AF530558, AC136829, FJ999701, CH474022 Ensembl: ENSRNOG00000002154 KO: rno:79110
Nucleutide sequences	EMBL-CDS: ACS37551.1, AAM94404.1, EDL99493.1, AAG33366.1, EDL99494.1, AAM94403.1 Ensembl_TRS: ENSRNOT00000091558
Protein sequencees	Ensembl_PRO: ENSRNOP00000074247 RefSeq: NP_077056.1, XP_006250697.1, XP_006250696.1
Others	UniRef100: UniRef100_A0A4X0WLY2, UniRef100_Q9ES02 UniRef90: UniRef90_Q9ES02 UniRef50: UniRef50_Q9ES02 UniGene: Rn.160717

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
27039006	Inherent physical characteristics and gene expression differences between alveolar and basal bones. Oral Surg Oral Med Oral Pathol Oral Radiol Ibrahim Zakhary , Fawwaz Alotibi , Jill Lewis , Mohammed ElSalanty , Karl Wenger , Mohamed Sharawy , Regina L W Messer	2016-07-01	-
24255709	Increased expression of matrix extracellular phosphoglycoprotein (MEPE) in cortical bone of the rat tibia after mechanical loading: identification by oligonucleotide microarray. PLoS ONE Christianne M A Reijnders , Huib W van Essen , Birgitte T T M van Rens , Johannes H G M van Beek , Bauke Ylstra , Marinus A Blankenstein , Paul Lips , Nathalie Bravenboer	2013-01-01	Mepe, MEPE
22766095	MEPE is a novel regulator of growth plate cartilage mineralization. Bone K A Staines , N C W Mackenzie , C E Clarkin , L Zelenchuk , P S Rowe , V E MacRae , C Farquharson	2012-09-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19617624	Molecular regulation of matrix extracellular phosphoglycoprotein expression by bone morphogenetic protein-2. J Biol Chem Young-Dan Cho , Won-Joon Yoon , Kyung-Mi Woo , Jeong-Hwa Baek , Gene Lee , Je-Yoel Cho , Hyun-Mo Ryoo	2009-09-11	-
19005008	Matrix extracellular phosphoglycoprotein inhibits phosphate transport. J. Am. Soc. Nephrol. Joanne Marks , Linda J Churchill , Edward S Debnam , Robert J Unwin	2008-12-01	Slc34a1, Mepe, MEPE
15843468	Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia. J. Am. Soc. Nephrol. Shiguang Liu , Thomas A Brown , Jianping Zhou , Zhou-Sheng Xiao , Hani Awad , Farshid Guilak , L Darryl Quarles	2005-06-01	Phex, Mepe
12421822	Targeted disruption of the osteoblast/osteocyte factor 45 gene (OF45) results in increased bone formation and bone mass. J Biol Chem Lori C Gowen , Donna N Petersen , Amy L Mansolf , Hong Qi , Jeffrey L Stock , George T Tkalcevic , Hollis A Simmons , David T Crawford , Kristen L Chidsey-Frink , Hua Zhu Ke , John D McNeish , Thomas A Brown	2003-01-17	-
10967096	Identification of osteoblast/osteocyte factor 45 (OF45), a bone-specific cDNA encoding an RGD-containing protein that is highly expressed in osteoblasts and osteocytes. J Biol Chem D N Petersen , G T Tkalcevic , A L Mansolf , R Rivera-Gonzalez , T A Brown	2000-11-17	-

研究热度

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