| Type | Description |
|---|---|
| Definition | ChaC glutathione specific gamma-glutamylcyclotransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 11:43:00 | Significant CHAC1 overexpression was detected in H. pylori-infected parietal cells that expressed the human proton pump/H,K-ATPase alpha subunit. | 31111570 |
| 2019-10-05 13:09:00 | results suggest that CHAC1 is involved in the regulation of inflammation in bronchial cells during Pseudomonas aeruginosa infection and may explain the excessive inflammation present in the respiratory tracts of patients with cystic fibrosis. | 30555487 |
| 2018-07-07 12:12:00 | The data revealed that CHAC2 prevented CHAC1-mediated GSH degradation, which suggests that CHAC2 competes with CHAC1 to maintain GSH homeostasis. | 29054545 |
| 2018-05-12 11:31:00 | Temozolomide (TMZ)-mediated gene expression profiles and networks are involved in inducing glioblastoma cell death. Increased CHAC1 and reduced Notch3 levels are both also significantly involved in TMZ-mediated cytotoxicity. The TMZ-regulated CHAC1 pathway inhibits Notch3 activation, resulting in attenuation of Notch3-mediated signaling pathways. | 27986595 |
| 2015-08-29 10:42:00 | Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the ATF4 and ATF3 and a Bipartite ATF/CRE | 25931127 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CHAC1_HUMAN
UniprotKB:
Q9BUX1
UniParc:
UPI00015DFCB6,
UPI000006F720
EMBL:
BC001683,
AC020661,
BC019625,
AY702027,
BC001847
Ensembl:
ENSG00000128965
KO:
hsa:79094
|
| Nucleutide sequences |
EMBL-CDS:
AAW23972.1,
AAH01683.1,
AAH19625.1,
AAH01847.1
Ensembl_TRS:
ENST00000617768,
ENST00000444189
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000395466,
ENSP00000484644
RefSeq:
XP_024305815.1,
NP_001136248.2,
XP_024305814.1,
XP_024305813.1,
NP_077016.3
|
| Others |
UniRef100:
UniRef100_Q9BUX1
UniRef90:
UniRef90_Q9BUX1
UniRef50:
UniRef50_Q9BUX1
UniGene:
Hs.155569
CCDS:
CCDS45233.1,
CCDS10070.3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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