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79071 ELOVL6

79071

ELOVL6

ELOVL fatty acid elongase 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition ELOVL fatty acid elongase 6

研究结论

Date Results Publications
2020-05-16 12:45:00 33 ELOVL6 mutations were found with a new variant in the promoter region, though no mutation in the coding region was found. However no mutations were found that largely deviated in allele frequency as compared with healthy Japanese individuals. 31956234
2019-10-19 12:01:00 our results indicate that Elovl6 enhances oncogenic activity in liver cancer and is associated with poor prognosis in patients with HCC. Elovl6 may be a therapeutic target for HCC 29700319
2017-12-09 12:10:00 Functional screening...revealed ELOVL6 as the main elongation enzyme responsible for acyl chain elongation in lung cancer squamous cell carcinoma cancer cells 26862848
2017-06-03 11:58:00 Ultra-high-throughput fluorescence screening followed by a RapidFire mass spectrometry assay was a suitable strategy for lead discovery against Elovl6. 27793673
2016-01-30 10:45:00 ). In conclusion, we found an interaction between the HLA-Cw6 and LCE genotypes on disease improvement among psoriatic patients treated with anti-TNFs. 25794162

名称对应

Type IDs
Synonymous FACE, FAE, LCE
Gene
UniProtKB-ID: ELOV6_HUMAN, A1LV06_HUMAN
UniprotKB: Q9H5J4, A1LV06
UniParc: UPI00000343F5
EMBL: CH471057, AC004050, AC093770, AK027031, BC001305, AK074813
Ensembl: ENSG00000170522
KO: hsa:79071
Nucleutide sequences
EMBL-CDS: BAB15632.1, BAC11225.1, AAH01305.1, AAY40928.1, EAX06260.1, EAX06259.1
Gene_ORFName: hCG_21424
Ensembl_TRS: ENST00000302274, ENST00000394607
Protein sequencees
Ensembl_PRO: ENSP00000304736, ENSP00000378105
RefSeq: XP_011530536.1, NP_076995.1, XP_011530535.1, NP_001124193.1
Others
UniRef100: UniRef100_Q9H5J4
UniRef90: UniRef90_Q9H5J4
UniRef50: UniRef50_Q9H5J4
UniGene: Hs.412939, Hs.652828
CCDS: CCDS3690.1

全选

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