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79066 METTL16

79066

METTL16

methyltransferase like 16

protein-coding

Homo sapiens

基因描述

Type Description
Definition methyltransferase like 16

研究结论

Date Results Publications
2020-09-12 16:05:00 Mechanistic insights into m6A modification of U6 snRNA by human METTL16. 32266935
2020-04-18 11:46:00 While METTL16 has been reported to be a nuclear protein, findings suggest that METTL16 is also a cytoplasmic methyltransferase that may alter its RNA binding preferences depending on its cellular localization. 31940410
2019-12-14 11:31:00 We speculate that m4C839 is involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits. Taken together our data show that METTL15 is a novel protein necessary for efficient translation in human mitochondria 31665743
2019-11-09 11:39:00 A native gel-shift assay shows that METTL16 binds to the MALAT1 RNA triple helix, but monomeric METTL16_291 does not. Results provide insights into the molecular structure of METTL16, which is distinct from METTL3/METTL14. 29593291
2018-07-21 11:29:00 Human METTL16 is a N(6)-methyladenosine methyltransferase that targets pre-mRNAs and various non-coding RNAs. 29051200

名称对应

Type IDs
Synonymous METT10D
Gene
UniProtKB-ID: MET16_HUMAN, B7Z3X7_HUMAN
UniprotKB: Q86W50, B7Z3X7
UniParc: UPI0000071A06, UPI0001914BAC, UPI0000200607
EMBL: AL832612, AK296464, CH471108, BC001213, AC006435, BC050603, AK027410, AC015799
Ensembl: ENSG00000127804
KO: hsa:79066
Nucleutide sequences
EMBL-CDS: AAH01213.1, BAB55094.1, EAW90537.1, CAD89999.2, AAH50603.1, EAW90538.1, BAH12363.1
Ensembl_TRS: ENST00000263092
Protein sequencees
Ensembl_PRO: ENSP00000263092
RefSeq: XP_005256858.1, XP_024306696.1, NP_076991.3, XP_016880535.1
Others
UniRef100: UniRef100_Q86W50
UniRef90: UniRef90_Q86W50
UniRef50: UniRef50_Q86W50
UniGene: Hs.632237
CCDS: CCDS42232.1

全选

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