| Type | Description |
|---|---|
| Definition | proline rich and Gla domain 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:30:00 | PRRG4 promotes breast cancer metastasis through the recruitment of NEDD4 and downregulation of Robo1. | 33037408 |
| 2017-09-23 10:21:00 | PRRG4 could re-localize hRobo1 from the cell surface, suggesting that PRRG4 is a functional homologue of Comm. Comm is required for axon guidance and synapse formation in the fly, so PRRG4 could contribute to the autistic symptoms of WAGR by disturbing either of these processes in the developing human brain. | 28859078 |
| 2014-11-08 10:56:00 | the unique genotype identified in this study suggested that haploinsufficiencies of PAX6 or PRRG4 included in this region are candidate genes for severe developmental delay and autistic features characteristic of WAGR syndrome. | 24357251 |
| 2014-02-08 10:13:00 | Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2. | 23873930 |
| Type | IDs |
|---|---|
| Synonymous | PRGP4, TMG4 |
| Gene |
UniProtKB-ID:
TMG4_HUMAN,
A0A0S2Z5N9_HUMAN
UniprotKB:
Q9BZD6,
A0A0S2Z5N9
UniParc:
UPI000013707A
EMBL:
CH471064,
BC010052,
AF326351,
KU178766,
BC063393
Ensembl:
ENSG00000135378
KO:
hsa:79056
|
| Nucleutide sequences |
EMBL-CDS:
AAH63393.1,
AAH10052.1,
AAK00956.1,
EAW68215.1,
ALQ34224.1
Gene_ORFName:
hCG_1644711
Ensembl_TRS:
ENST00000257836
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000257836
RefSeq:
XP_006718377.1,
NP_076986.1,
XP_006718376.3
|
| Others |
UniRef100:
UniRef100_Q9BZD6
UniRef90:
UniRef90_Q9BZD6
UniRef50:
UniRef50_Q9BZD6
UniGene:
Hs.471695
CCDS:
CCDS7881.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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