| Type | Description |
|---|---|
| Definition | PVR related immunoglobulin domain containing |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:13:00 | we demonstrate that PVRIG and PVRL2 are expressed in human cancers and the PVRIG-PVRL2 and TIGIT-PVR pathways are nonredundant inhibitory signaling pathways. | 30659054 |
| 2017-12-09 11:54:00 | Blockade of TIGIT or CD112R, separately or together, enhances trastuzumab-triggered antitumor response by human NK cells. | 28623459 |
| 2016-08-20 12:22:00 | Describe CD112R, a member of poliovirus receptor-like proteins, as a new coinhibitory receptor for T cells. CD112R is preferentially expressed on T cells and inhibits T cell receptor-mediated signals. | 26755705 |
| Type | IDs |
|---|---|
| Synonymous | C7orf15, CD112R |
| Gene |
UniProtKB-ID:
PVRIG_HUMAN
UniprotKB:
Q6DKI7
UniParc:
UPI000013FFF0
EMBL:
BC001129,
BC073861,
BC107873,
CH471091
Ensembl:
ENSG00000213413
KO:
hsa:79037
|
| Nucleutide sequences |
EMBL-CDS:
AAH01129.1,
EAW76566.1,
AAI07874.1,
EAW76567.1,
AAH73861.1
Ensembl_TRS:
ENST00000317271
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000316675
RefSeq:
NP_001374063.1,
XP_011514877.1,
NP_076975.2
|
| Others |
UniRef100:
UniRef100_Q6DKI7
UniRef90:
UniRef90_Q6DKI7
UniRef50:
UniRef50_Q6DKI7
UniGene:
Hs.729356
CCDS:
CCDS5690.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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