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79031 PDCL3

79031

PDCL3

phosducin like 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosducin like 3

研究结论

Date Results Publications
2017-11-04 12:33:00 results have shown that PhLP2A interacts with Hsp90 and exhibits molecular chaperone activity toward denatured proteins. 27496612
2017-09-23 12:52:00 family-based GWAS of imputed SNPs revealed novel genomic variants in (or near) PTPRG, OSBPL6, and PDCL3 that influence risk for Alzheimer's Disease. rs7609954 in the gene PTPRG, rs1347297 in the gene OSBPL6, and rs1513625 near PDCL3. In addition, rs72953347 in OSBPL6 and two SNPs in the gene CDKAL1 showed marginally significant association with LOAD (rs10456232, P-value=4.76 x 10-7; rs62400067, P-value=3.54 x 10-7). 26830138
2016-08-06 11:21:00 The data provide new insights for the chaperone function of PDCL3 in angiogenesis and the roles of hypoxia and N-terminal methionine acetylation in PDCL3 expression and its effect on VEGFR-2. 26059764
2013-11-02 10:57:00 data provide strong evidence for the role of PDCL3 in angiogenesis and establishes the molecular mechanism by which it regulates VEGFR-2 expression and function. 23792958
2010-01-21 00:00:00 Data support a model in which Plp2p modulates the biogenesis of several CCT substrates relating to cell cycle and cytoskeletal function, which together contribute to the essential function of PLP2. 17429077

名称对应

Type IDs
Synonymous HTPHLP, PHLP2A, PHLP3, VIAF, VIAF1
Gene
UniProtKB-ID: PDCL3_HUMAN
UniprotKB: Q9H2J4
UniParc: UPI00000372D0
EMBL: CH471127, AK313985, AF267853, AF110511, AC068538, BC001021
Ensembl: ENSG00000115539
KO: hsa:79031
Nucleutide sequences
EMBL-CDS: AAG21887.1, BAG36697.1, AAG44722.1, AAH01021.1, AAX93227.1, EAX01838.1
Ensembl_TRS: ENST00000264254
Protein sequencees
Ensembl_PRO: ENSP00000264254
RefSeq: XP_016860379.1, NP_076970.1
Others
UniRef100: UniRef100_Q9H2J4
UniRef90: UniRef90_Q9H2J4
UniRef50: UniRef50_Q9H2J4
UniGene: Hs.469459
CCDS: CCDS33261.1

全选

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