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79026 AHNAK

79026

AHNAK

AHNAK nucleoprotein

protein-coding

Homo sapiens

基因描述

Type Description
Definition AHNAK nucleoprotein

研究结论

Date Results Publications
2021-02-13 13:20:00 SORBS1 serves a metastatic role via suppression of AHNAK in colorectal cancer cell lines. 32319594
2020-10-24 13:59:00 CircAHNAK1 inhibits proliferation and metastasis of triple-negative breast cancer by modulating miR-421 and RASA1. 31857500
2020-04-18 10:12:00 High AHNAK expression is associated with metastasis in Castration-Resistant Prostate Cancer. 31110158
2019-12-21 10:36:00 Results showed that AHNAK methylation level in PBMC decreases with the exacerbation of HBV related liver disease, suggesting a certain correlation between AHNAK methylation and the progression of liver disease providing a potential differential diagnostic method for HBV-related hepatopathies, and an early detective tool for liver cancer. 30259695
2019-11-09 12:11:00 Data show that AHNAK is a direct substrate of UBE3C, which elevated levels controlled the basal turnover of AHNAK by ubiquitin-mediated proteolysis. Elevated AHNAK levels and lower UBE3C levels predict better patient survival and might represent a prognostic marker in non-small-cell lung cancer (NSCLC). AHNAK is required for p53 binding to the promoter regions of stemness- related genes, thereby controlling cell stemness. 30503554

名称对应

Type IDs
Synonymous AHNAKRS, PM227
Gene
UniProtKB-ID: AHNK_HUMAN, B4DTV0_HUMAN, Q9BVU3_HUMAN
UniprotKB: Q09666, B4DTV0, Q9BVU3
UniParc: UPI000006EA02, UPI00017A7EA7, UPI00004EC29C, UPI000013CF51
EMBL: CH471076, AK300376, BC000926, BC128460, AP003064, AP001363, M80899, M80902
Ensembl: ENSG00000124942
KO: hsa:79026
Nucleutide sequences
EMBL-CDS: AAI28461.1, AAA69899.1, AAA69898.1, EAW74019.1, BAG62112.1, AAH00926.1
Ensembl_TRS: ENST00000378024, ENST00000257247
Protein sequencees
Ensembl_PRO: ENSP00000257247, ENSP00000367263
RefSeq: NP_076965.2, NP_001333375.1, XP_016873759.1, NP_001611.1, NP_001333374.1
Others
UniRef100: UniRef100_B4DTV0, UniRef100_Q09666, UniRef100_Q9BVU3
UniRef90: UniRef90_Q09666, UniRef90_B4DTV0, UniRef90_Q09666-2
UniRef50: UniRef50_Q09666, UniRef50_Q09666-2, UniRef50_B4DTV0
UniGene: Hs.502756
CCDS: CCDS31584.1, CCDS44625.1

全选

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