| Type | Description |
|---|---|
| Definition | gamma-glutamylcyclotransferase |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:29:00 | gamma-Glutamyl cyclotransferase contributes to endometrial carcinoma malignant progression and upregulation of PD-L1 expression during activation of epithelial-mesenchymal transition. | 31757677 |
| 2020-07-04 11:27:00 | a role for EP2/EP4 signaling in regulating IGF-1-induced cell proliferation, in which EP2/EP4 signaling represses IGF-1-induced GGCT expression, is reported. | 31217077 |
| 2020-06-13 12:25:00 | FOXO3a is identified as a mediator for p21 upregulation by GGCT depletion. AMPK is required for the FOXO3a-mediated p21 upregulation by GGCT depletion. AMPK-FOXO3a-p21 axis plays a role in cancer cell growth inhibition by GGCT depletion. | 31345573 |
| 2018-07-14 11:01:00 | GGCT is highly upregulated in HGSC tissues and associated with FIGO stage, lymph node metastasis and ascitic fluid volume. High expression of GGCT is associated with poor survival in HGSC patients. | 29429592 |
| 2018-02-17 10:48:00 | Taken together, the results indicate that PHB2 plays a central role in p21 upregulation following GGCT knockdown and as such may promote deregulated proliferation of cancer cells by suppressing p21. | 29307834 |
| Type | IDs |
|---|---|
| Synonymous | C7orf24, CRF21, GCTG, GGC |
| Gene |
UniProtKB-ID:
GGCT_HUMAN,
A0A090N7V5_HUMAN
UniprotKB:
O75223,
A0A090N7V5
UniParc:
UPI000020ED09,
UPI0000070090,
UPI00000473DC,
UPI000020ED05
EMBL:
BC013937,
BC005356,
BC019243,
AACC02000087,
BC000625,
AK315608,
CH471073,
AC005154
Ensembl:
ENSG00000006625
KO:
hsa:79017
|
| Nucleutide sequences |
EMBL-CDS:
EAW93950.1,
EAW93952.1,
AAH05356.1,
AAH19243.1,
AAH13937.1,
EAW93953.1,
BAG37977.1,
AAH00625.1,
EAL24452.1
Gene_ORFName:
tcag7.1010
Ensembl_TRS:
ENST00000005374,
ENST00000409390,
ENST00000275428,
ENST00000409144
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000005374,
ENSP00000386610,
ENSP00000387235,
ENSP00000275428
RefSeq:
NP_001186746.1,
NP_001186744.1,
NP_001186745.1,
NP_076956.1
|
| Others |
UniRef100:
UniRef100_O75223
UniRef90:
UniRef90_O75223
UniRef50:
UniRef50_O75223
UniGene:
Hs.530024
CCDS:
CCDS56475.1,
CCDS5428.1,
CCDS56474.1,
CCDS56476.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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