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79016 DDA1

79016

DDA1

DET1 and DDB1 associated 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition DET1 and DDB1 associated 1

研究结论

Date Results Publications
2018-08-04 10:37:00 surveyed the spectrum of G protein coupling of dDA1 and Damb, and we confirmed that both receptors can couple to Gs to stimulate cAMP synthesis 29166600
2018-04-21 10:15:00 The results indicate that DDA1 promotes lung cancer progression, potentially through promoting cyclins and cell cycle progression. 28211159
2017-12-02 11:07:00 Data indicate that DET1- and DDB1-associated protein 1 (DDA1)-mediated tumor progression is associated with the activation of the NF-kappa B (NFkappaB)/COP9 signalosome 2(CSN2)/glycogen synthase kinase3beta (GSK3beta) pathway. 26942699
2017-07-10 17:53:00 the c-Abl non-receptor kinase phosphorylates DDB1 at residue Tyr-316 to recruit a small regulatory protein, DDA1, leading to increased substrate ubiquitination 28087699
2010-01-21 00:00:00 Cells depleted of Dda1 spontaneously accumulated double-stranded DNA breaks in a similar way to Cul4A-, Cul4B- or Wdr23-depleted cells, indicating that Dda1 interacts physically and functionally with cullin-RING E3 ligases complexes. 19295130

名称对应

Type IDs
Synonymous C19orf58, PCIA1
Gene
UniProtKB-ID: DDA1_HUMAN, A0A024R7J7_HUMAN
UniprotKB: Q9BW61, A0A024R7J7
UniParc: UPI0000071D06
EMBL: AY563006, BC000615, DQ090952, CH471106
Ensembl: ENSG00000130311
KO: hsa:79016
Nucleutide sequences
EMBL-CDS: AAZ41375.1, AAH00615.1, EAW84593.1, AAS66629.1, EAW84594.1
Gene_ORFName: hCG_2039968
Ensembl_TRS: ENST00000593466, ENST00000596582, ENST00000359866
Protein sequencees
Ensembl_PRO: ENSP00000472171, ENSP00000352928, ENSP00000473086
RefSeq: XP_024307469.1, NP_076955.1
Others
UniRef100: UniRef100_Q9BW61
UniRef90: UniRef90_Q9BW61
UniRef50: UniRef50_Q9BW61
UniGene: Hs.466154
CCDS: CCDS12357.1

全选

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