| Type | Description |
|---|---|
| Definition | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:11:00 | Activation and selectivity of OTUB-1 and OTUB-2 deubiquitinylases. | 32265297 |
| 2019-12-07 11:31:00 | Taken together, the present study provides the first evidence that OTUB2 acts as a pivotal driver in non-small cell lung cancer tumorigenesis by stabilizing U2AF2 and activating the AKT/mTOR pathway and the Warburg effect. | 30662561 |
| 2019-06-08 10:54:00 | By elucidating a novel SUMOylation-mediated control mechanism of YAP/TAZ signaling in breast cancer metastasis, we have revealed previously unknown interplay between oncogenic KRAS and EGFR signaling and YAP/TAZ protein stability. | 30472188 |
| 2019-06-01 10:49:00 | Data indicate the eubiquitinating enzyme otubain2 (OTUB2) as a regulator of GLI family zinc finger 2 (Gli2) protein degradation. | 30241937 |
| 2014-04-26 12:33:00 | OTUB2 fine-tunes the speed of double-strand break-induced ubiquitination so that the appropriate DNA repair pathway is chosen | 24560272 |
| Type | IDs |
|---|---|
| Synonymous | C14orf137, OTB2, OTU2 |
| Gene |
UniProtKB-ID:
OTUB2_HUMAN
UniprotKB:
Q96DC9
UniParc:
UPI000000D869,
UPI0000070517
EMBL:
BC009615,
AL079302,
CR457345,
AK025569,
AY177201,
BC068058
Ensembl:
ENSG00000089723,
ENSG00000277276
KO:
hsa:78990
|
| Nucleutide sequences |
EMBL-CDS:
AAH68058.1,
CAG33626.1,
AAH09615.1,
AAO27703.1,
BAB15172.1
Ensembl_TRS:
ENST00000203664,
ENST00000553723,
ENST00000628711,
ENST00000617748
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000451283,
ENSP00000487491,
ENSP00000203664,
ENSP00000478628
RefSeq:
NP_075601.1
|
| Others |
UniRef100:
UniRef100_Q96DC9
UniRef90:
UniRef90_Q96DC9
UniRef50:
UniRef50_Q96DC9
UniGene:
Hs.278815
CCDS:
CCDS9917.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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