| Type | Description |
|---|---|
| Definition | apoptotic peptidase activating factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:43:00 | CARD9 protects cardiomyocytes from apoptosis by interacting with Apaf-1 and interfering with apoptosome formation following myocardial ischemia/reperfusion injury in vivo and in vitro | 31212066 |
| 2018-06-02 11:46:00 | ZYZ-488 as a novel small molecule competitive inhibitor of Apaf-1, with the great potential for treating cardiac ischemia. | 27443636 |
| 2017-08-12 11:14:00 | miR-183 was induced in protective postconditioning and reduced reperfusion injury of the livers via the targeting of apoptotic signaling. miR-183 mediated the tolerance induced by iPoC in livers via Apaf-1 repressing. | 27580417 |
| 2015-11-14 11:00:00 | MicroRNA-17-mediated down-regulation of Apaf-1 attenuates apoptosome formation and subsequent apoptosis of cardiomyocytes. | 26265044 |
| 2015-07-04 12:13:00 | results provide evidence that Apaf-1 pharmacological inhibition has therapeutic potential for the treatment of apoptosis-related diseases. | 25330150 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
APAF_RAT
UniprotKB:
Q9EPV5
UniParc:
UPI0000125BF1
EMBL:
AF320222
Ensembl:
ENSRNOG00000008022
KO:
rno:78963
|
| Nucleutide sequences |
EMBL-CDS:
AAG35067.1
Ensembl_TRS:
ENSRNOT00000010869
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000010869
RefSeq:
NP_076469.1,
XP_008763485.1
|
| Others |
UniRef100:
UniRef100_Q9EPV5
UniRef90:
UniRef90_O88879
UniRef50:
UniRef50_O14727
UniGene:
Rn.64522
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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