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78920 Dlst

78920

Dlst

dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

protein-coding

Mus musculus

基因描述

Type Description
Definition dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

研究结论

Date Results Publications
2017-09-16 11:19:00 DLST protein levels were decreased on pressure overload in wild-type mice, but levels were maintained in microRNA-146a knock-out mice. 28611091
2013-08-03 12:00:00 ATP consumption is demonstrated in respiration-impaired isolated and in situ neuronal somal mitochondria from transgenic mice with a deficiency of dihydrolipoyl dehydrogenase. 23475850
2012-01-28 11:25:00 These results imply that diminished KGDHC activity has the potential to induce the reduction in glucose utilization that is seen in several neurodegenerative diseases. 21374701
2010-06-14 11:02:00 A reduction in the DLST subunit of alpha-ketoglutarate dehydrogenase complex (KGDHC) alters the overall KGDHC activity and susceptibility to mitochondrial toxins and may contribute to the pathogenesis of neurodegenerative diseases. 19660549

名称对应

Type IDs
Synonymous 1600017E01Rik, 4632413C10Rik, 4930529O08Rik, DLTS
Gene
UniProtKB-ID: ODO2_MOUSE
UniprotKB: Q9D2G2
UniParc: UPI0000020E2F, UPI00000E8C75
EMBL: AK149664, AK168570, CT010197, BC006702, AK019713, AK054053, AK158877, BC024066, AK169943
Ensembl: ENSMUSG00000004789
KO: mmu:78920
Nucleutide sequences
EMBL-CDS: AAH24066.1, BAE41472.1, BAE34709.1, CAJ18405.1, BAE29011.1, AAH06702.1, BAE40440.1, BAB31840.1, BAC35637.1
Ensembl_TRS: ENSMUST00000221357, ENSMUST00000053811
Protein sequencees
Ensembl_PRO: ENSMUSP00000060346, ENSMUSP00000152664
RefSeq: NP_084501.1, XP_006516455.1
Others
UniRef100: UniRef100_Q9D2G2
UniRef90: UniRef90_Q9D2G2
UniRef50: UniRef50_Q9D2G2
UniGene: Mm.296221
CCDS: CCDS26052.1

全选

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