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78688 Nol3

78688

Nol3

nucleolar protein 3 (apoptosis repressor with CARD domain)

protein-coding

Mus musculus

基因描述

Type Description
Definition nucleolar protein 3 (apoptosis repressor with CARD domain)

研究结论

Date Results Publications
2019-03-23 11:34:00 our data revealed the pivotal role of ARC in myocardial necrosis and delineated the p53-ARC-CypD/mPTP central necrosis pathway, which can provide a potential therapeutic avenue for ischemia and oxidative stress-related cardiac diseases. 30415165
2019-03-08 17:28:00 Soleus of ARC-deficient mice exhibited lower total, as well as fiber type-specific cross sectional area in type I and IIA skeletal muscle fibers. 25596718
2018-02-17 10:08:00 Data suggest that reduced levels of apoptosis repressor with caspase recruitment domain protein (ARC) might correlate with neomycin-induced hair cells (HCs) loss. 27556499
2016-07-16 11:05:00 Although mice lacking Men1 developed insulinomas as expected, elimination of ARC in this context did not significantly alter tumor load. Cellular rates of proliferation and death in these tumors were also not perturbed in the absence of ARC. 26709830
2014-11-08 10:47:00 interaction of ARC with TNF receptor 1 Interferes with recruitment of RIP1, a critical mediator of TNFalpha-induced regulated necrosis. 24440909

名称对应

Type IDs
Synonymous ARC, B430311C09Rik, MYC, NOP, Nop30
Gene
UniProtKB-ID: NOL3_MOUSE, Q53YU5_MOUSE
UniprotKB: Q9D1X0, Q53YU5
UniParc: UPI00000040D9
EMBL: AK021023, AK053846, AY459322
Ensembl: ENSMUSG00000014776
KO: mmu:78688
Nucleutide sequences
EMBL-CDS: BAB32281.1, AAR22550.1, BAC35554.1
Ensembl_TRS: ENSMUST00000014920
Protein sequencees
Ensembl_PRO: ENSMUSP00000014920
RefSeq: XP_006531566.1, NP_084428.1
Others
UniRef100: UniRef100_Q9D1X0
UniRef90: UniRef90_Q62881
UniRef50: UniRef50_Q62881
UniGene: Mm.475715
CCDS: CCDS52657.1

全选

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研究热度

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