| Type | Description |
|---|---|
| Definition | frizzled class receptor 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:09:00 | FZD5 contributes to TNBC proliferation, DNA damage repair and stemness. | 33311446 |
| 2021-02-13 13:28:00 | Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling. | 32762848 |
| 2019-10-26 12:41:00 | Study shows that FZD5 exhibited a conformational change after the addition of WNT-5A, FZD5 activated Galphaq and its downstream effectors upon stimulation. | 30514810 |
| 2019-10-26 10:31:00 | The current study demonstrates a pro-angiogenic role of Fzd5, which was shown to be involved in endothelial tubule formation, cell cycle progression and migration, and partly does so by repression of transcription of Flt1 and Angpt2. | 29845518 |
| 2019-09-07 11:44:00 | Results showed that mRNA expression of FZD5 was upregulated in nasal polyps and significantly higher in nasal polyp samples from patients with eosinophilic chronic rhinosinusitis (CRSwNP) than in those with non-eosinophilic CRSwNP. These findings demonstrate that FZD5 expression in nasal mucosal epithelial cells is correlated with inflammatory cells and might play a role in the pathogenesis of eosinophilic CRSwNP. | 31082802 |
| Type | IDs |
|---|---|
| Synonymous | C2orf31, HFZ5 |
| Gene |
UniProtKB-ID:
FZD5_HUMAN
UniprotKB:
Q13467
UniParc:
UPI000013E255
EMBL:
AK290386,
AK315338,
AC096772,
U43318,
AB043702
Ensembl:
ENSG00000163251
KO:
hsa:7855
|
| Nucleutide sequences |
EMBL-CDS:
AAY24058.1,
AAC50385.1,
BAF83075.1,
BAG37738.1,
BAB60959.1
Ensembl_TRS:
ENST00000295417
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354607
RefSeq:
XP_024308898.1,
NP_003459.2
|
| Others |
UniRef100:
UniRef100_Q13467
UniRef90:
UniRef90_Q9EQD0
UniRef50:
UniRef50_Q9EQD0
UniGene:
Hs.17631
CCDS:
CCDS33366.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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