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7846 TUBA1A

7846

TUBA1A

tubulin alpha 1a

protein-coding

Homo sapiens

基因描述

Type Description
Definition tubulin alpha 1a

研究结论

Date Results Publications
2021-01-09 13:26:00 Microcephaly with a simplified gyral pattern in a child with a de novo TUBA1A variant. 31833200
2020-11-28 13:16:00 Mutations disrupting neuritogenesis genes confer risk for cerebral palsy. 32989326
2020-09-19 16:27:00 Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. 31767681
2020-04-04 13:04:00 the palmitoylation level of Rasrelated protein Rab7a (Rab7a) was enhanced by androgen treatment. Palmitoylation of alphatubulin and Rab7a were essential for cell proliferation. Notably, in the supernatant of LNCaP cells, the palmitoylation level of alphatubulin was also increased following androgen treatment. Palmitoylation of alphatubulin may provide a new potential target for the treatment of prostate cancer. 31578588
2020-02-29 10:40:00 This study examined the crystal structures of human vasohibin 1 and 2 in complex with small vasohibin-binding protein (SVBP) in the absence and presence of different inhibitors and a C-terminal alpha-tubulin peptide. 31235911

名称对应

Type IDs
Synonymous B-ALPHA-1, LIS3, TUBA3
Gene
UniProtKB-ID: TBA1A_HUMAN
UniprotKB: Q71U36
UniParc: UPI00005A4BF8, UPI0000000DB2
EMBL: BC006468, X01703, K00557, CH471111, AC010173, BC050637, AF141347, AK289483
Ensembl: ENSG00000167552
KO: hsa:7846
Nucleutide sequences
EMBL-CDS: BAF82172.1, AAH50637.1, EAW58052.1, CAA25855.1, EAW58054.1, AAA91575.1, AAH06468.1, EAW58055.1, AAD33871.1
Ensembl_TRS: ENST00000301071, ENST00000295766, ENST00000550767
Protein sequencees
Ensembl_PRO: ENSP00000439020, ENSP00000301071, ENSP00000446637
RefSeq: NP_001257328.1, NP_006000.2, NP_001257329.1
Others
UniRef100: UniRef100_Q71U36
UniRef90: UniRef90_Q71U36
UniRef50: UniRef50_Q71U36
UniGene: Hs.654422
CCDS: CCDS58226.1, CCDS8781.1, CCDS58227.1

全选

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