| Type | Description |
|---|---|
| Definition | major vault protein |
| Date | Results | Publications |
|---|---|---|
| 2019-10-05 12:44:00 | MVP regulates activity-dependent synaptic plasticity in mouse visual cortex. | 29540554 |
| 2019-05-25 11:04:00 | Study identified major vault protein (MVP) as a suppressor for NF-kappaB signaling in macrophages. Both global and myeloid-specific MVP gene knockout aggravates high-fat diet induced obesity, insulin resistance, hepatic steatosis and atherosclerosis in mice. Results demonstrate that macrophage MVP constitutes a key constraint of NF-kappaB signaling thereby suppressing metabolic diseases. | 30996248 |
| 2016-08-20 10:14:00 | plays major role in anti-viral immunity | 26843330 |
| 2013-09-14 10:42:00 | MVP may fine-tune SR-A activity in macrophages which contributes to the development of atherosclerosis | 23703615 |
| 2011-12-03 10:51:00 | MVP is hijacked by L. monocytogenes in order to counteract the autophagy process, a finding that could have major implications in deciphering the cellular role of vault particles. | 21829365 |
| Type | IDs |
|---|---|
| Synonymous | 2310009M24Rik, LRP, VAULT1 |
| Gene |
UniProtKB-ID:
MVP_MOUSE,
E9Q3X0_MOUSE,
Q3U7S9_MOUSE
UniprotKB:
Q9EQK5,
E9Q3X0,
Q3U7S9
UniParc:
UPI00005ACBF4,
UPI000056405C,
UPI0000023586
EMBL:
CH466531,
AY046318,
AF210456,
AC122863,
AK152534,
BC006709
Ensembl:
ENSMUSG00000030681
KO:
mmu:78388
|
| Nucleutide sequences |
EMBL-CDS:
AAG43520.1,
AAH06709.1,
EDL17488.1,
AAL02325.1,
EDL17489.1,
BAE31290.1
Ensembl_TRS:
ENSMUST00000165096
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000127250
RefSeq:
XP_011240254.1,
NP_542369.2
|
| Others |
UniRef100:
UniRef100_Q9EQK5
UniRef90:
UniRef90_Q9EQK5
UniRef50:
UniRef50_Q9EQK5
UniGene:
Mm.228797
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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