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7805 LAPTM5

7805

LAPTM5

lysosomal protein transmembrane 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition lysosomal protein transmembrane 5

研究结论

Date Results Publications
2017-12-16 10:49:00 These findings suggest that the inactivation of LAPTM5 may contribute to tumorigenesis in a subset of human cancers 27058622
2017-04-08 10:10:00 Taken together, our results suggested that decreased LAPTM5 inhibited proliferation and viability, as well as induced G0/G1 cell cycle arrest possibly via deactivation of ERK1/2 and p38 in BCa cells 27922670
2016-01-02 12:03:00 Insufficient expression of LAPTM5 may take part in the pathogenesis of systemic lupus erythematosus (SLE) and contribute to the severity of the disease, none of LAPTM5 polymorphisms contributes significantly to SLE susceptibility in a Chinese population. 25998573
2013-01-12 11:15:00 The interaction of LAPTM5 with CD1e and their colocalization in antigen processing compartments both suggest that LAPTM5 might influence the role of CD1e in the presentation of lipid antigens. 22880058
2012-02-25 10:58:00 LAPTM5 is a substrate of the ITCH-mediated degradation and its protein level is negatively regulated by ITCH 22009753

名称对应

Type IDs
Synonymous CLAST6
Gene
UniProtKB-ID: LAPM5_HUMAN, Q5TBB8_HUMAN
UniprotKB: Q13571, Q5TBB8
UniParc: UPI000012E20A
EMBL: AK292009, CH471059, BC106896, U51240, BC106897, U30498, D42042
Ensembl: ENSG00000162511
KO: hsa:7805
Nucleutide sequences
EMBL-CDS: AAB08975.1, AAI06897.1, BAA07643.1, AAA74018.1, EAX07641.1, AAI06898.1, BAF84698.1, EAX07640.1
Gene_ORFName: hCG_15079
Ensembl_TRS: ENST00000294507
Protein sequencees
Ensembl_PRO: ENSP00000294507
RefSeq: NP_006753.1, XP_011540400.1
Others
UniRef100: UniRef100_Q13571
UniRef90: UniRef90_Q13571
UniRef50: UniRef50_Q13571
UniGene: Hs.371021
CCDS: CCDS337.1

全选

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