| Type | Description |
|---|---|
| Definition | LDL receptor related protein 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:55:00 | Further evidence for the association between LRP8 and schizophrenia. | 28495490 |
| 2020-11-28 13:17:00 | Genome-scale CRISPR activation screening identifies a role of LRP8 in Sorafenib resistance in Hepatocellular carcinoma. | 32312520 |
| 2020-03-07 10:42:00 | Our findings suggest that new approaches targeting LRP8 may constitute promising treatments for hormone-negative breast cancers, those overexpressing HER2 and TNBCs. | 30575334 |
| 2019-10-05 11:52:00 | Data indicate low-density lipoprotein receptor-related protein 8 (LRP8) as a therapeutic target for triple-negative breast cancer (TNBC) as inhibition of LRP8 can attenuate Wnt/beta-catenin signaling to suppress breast cancer stem cells (BCSCs). | 30227220 |
| 2019-03-23 12:21:00 | CSF-ApoER2 fragments as a read-out of reelin signaling: Distinct patterns in sporadic and autosomal-dominant Alzheimer disease | 30552869 |
| Type | IDs |
|---|---|
| Synonymous | APOER2, HSZ75190, LRP-8, MCI1 |
| Gene |
UniProtKB-ID:
LRP8_HUMAN,
A0A590UJ98_HUMAN
UniprotKB:
Q14114,
A0A590UJ98
UniParc:
UPI00001AF333,
UPI00004561DF,
UPI00001AF338,
UPI00001AEE1A,
UPI000041FF0D
EMBL:
D50678,
BC051836,
AL355483,
Z75190,
BC006443,
AL606760,
D86407
Ensembl:
ENSG00000157193
KO:
hsa:7804
|
| Nucleutide sequences |
EMBL-CDS:
BAA09328.1,
AAH06443.1,
BAA21824.1,
CAA99509.1,
AAH51836.2,
BAA21825.1
Ensembl_TRS:
ENST00000347547,
ENST00000354412,
ENST00000371454,
ENST00000306052,
ENST00000662198
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000303634,
ENSP00000334522,
ENSP00000346391,
ENSP00000360509,
ENSP00000499355
RefSeq:
NP_001018064.1,
XP_005271231.1,
XP_016857756.1,
NP_150643.2,
XP_011540396.1,
XP_005271230.1,
XP_005271232.1,
NP_004622.2,
XP_016857757.1,
XP_016857755.1,
XP_011540397.1,
XP_011540398.1,
XP_006710944.1,
XP_016857754.1,
XP_006710945.1,
NP_059992.3
|
| Others |
UniRef100:
UniRef100_Q14114,
UniRef100_A0A590UJ98
UniRef90:
UniRef90_Q14114,
UniRef90_Q14114-3
UniRef50:
UniRef50_Q14114,
UniRef50_Q924X6
UniGene:
Hs.280387
CCDS:
CCDS580.1,
CCDS30720.1,
CCDS578.1,
CCDS579.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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