| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase 4A1 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-05 10:12:00 | These results provide evidence indicating a regulatory role of PRL-1 during Immunological Synapse assembly and highlight the involvement of PRLs in immune responses by mature T cells. | 30515156 |
| 2019-02-02 12:03:00 | Overexpression of miR-339-5p enhanced radiosensitivity of A549 and H460 cells by inhibiting cell viability, increasing apoptosis, inducing cell cycle arrest, and suppressing cell proliferation. Further exploration validated that miR-339-5p can target phosphatases of regenerating liver-1 (PRL-1) in lung cancer cells. | 30462625 |
| 2019-01-12 11:54:00 | PRL mRNA transcription was stimulated by Mg(2+) depletion. A series of analyses revealed the activation and the crucial importance of signal transducer and activator of transcription 1 in this process. Collectively, these results implicate PRL in maintaining cellular Mg(2+) homeostasis. | 29487165 |
| 2018-08-11 11:48:00 | PTP4A1 is a direct downstream target of miR-1271 in the hepatocellular carcinoma. | 29345291 |
| 2018-05-05 10:43:00 | PTP4A1 is highly expressed in fibroblasts from patients with systemic sclerosis and enhances pro-fibrotic TGFbeta signaling in these cells. | 29057934 |
| Type | IDs |
|---|---|
| Synonymous | HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1 |
| Gene |
UniProtKB-ID:
TP4A1_HUMAN,
A0A024R8J2_HUMAN
UniprotKB:
Q93096,
A0A024R8J2
UniParc:
UPI00000227B8
EMBL:
CR749458,
AF051160,
AL135905,
U48296,
BC045571,
BC023975,
AK312526,
U69701,
CH471143
Ensembl:
ENSG00000112245
KO:
hsa:7803
|
| Nucleutide sequences |
EMBL-CDS:
AAH23975.1,
AAB40597.1,
AAH45571.1,
EAW88494.1,
AAB09080.1,
BAG35425.1,
CAH18292.1,
AAC39836.1,
EAW88495.1
Gene_ORFName:
hCG_1758968
Ensembl_TRS:
ENST00000626021,
ENST00000672924,
ENST00000673199,
ENST00000648894
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000500859,
ENSP00000485687,
ENSP00000500952,
ENSP00000497588
RefSeq:
NP_001372186.1,
NP_001372197.1,
NP_001372191.1,
NP_001372187.1,
NP_001372184.1,
NP_001372185.1,
NP_001372194.1,
NP_001372188.1,
NP_001372196.1,
NP_001372192.1,
NP_001372189.1,
XP_011534413.1,
NP_003454.1,
NP_001372195.1,
NP_001372183.1
|
| Others |
UniRef100:
UniRef100_Q93096
UniRef90:
UniRef90_Q93096
UniRef50:
UniRef50_Q93096
UniGene:
Hs.227777,
Hs.706850
CCDS:
CCDS4965.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员