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7799 PRDM2

7799

PRDM2

PR/SET domain 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition PR/SET domain 2

研究结论

Date Results Publications
2020-04-11 11:13:00 PRDM2 negatively regulated the expression of c-Myc in somatotroph adenomas, and testified the synergism between PRDM2 gene therapy and c-Myc inhibitor in vitro experiment 32044406
2018-12-22 10:20:00 The authors have found that overexpression of RIZ1 in HEK293 cells reduced the expression of Akt3 protein. 29367689
2018-04-14 11:51:00 Promoter hypermethylation may play an important role in the epigenetic silencing of RIZ1 expression in human glioma tissues and glioblastoma cell lines. 27757741
2018-01-13 14:21:00 the Pro704 p-/- allele of RIZ is significantly more common in CML patients with Loss of hematological response than good responders (p = .001). We showed that LOH p-/- homozygosity of RIZ1 was common event in BC than proline p+/+ homozygosity and proline p+/+ homozygosity more common feature in CP phase CML. 27830966
2017-07-29 13:08:00 Promoter region methylation of RIZ1 may play an important role in the epigenetic silencing of RIZ1 expression in pituitary adenomas, which may translate into important diagnostic and therapeutic applications 28718376

名称对应

Type IDs
Synonymous HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2
Gene
UniProtKB-ID: PRDM2_HUMAN
UniprotKB: Q13029
UniParc: UPI0000D7A4FB, UPI000013C9CD, UPI000013F0E4, UPI000006DC3B, UPI00001408AA
EMBL: D45132, BC014468, AL583942, AL359771, BX647310, U17838, U23736, AL031277
Ensembl: ENSG00000116731
KO: hsa:7799
Nucleutide sequences
EMBL-CDS: AAA87023.1, BAA08110.1, AAC50820.2
Ensembl_TRS: ENST00000376048, ENST00000235372, ENST00000311066, ENST00000343137, ENST00000413440
Protein sequencees
Ensembl_PRO: ENSP00000341621, ENSP00000365216, ENSP00000411103, ENSP00000235372, ENSP00000312352
RefSeq: XP_016857751.1, XP_016857746.1, XP_016857748.1, XP_016857749.1, XP_016857750.1, XP_016857745.1, NP_001129082.1, NP_001007258.1, XP_016857744.1, XP_016857753.1, XP_016857752.1, NP_056950.2, NP_036363.2
Others
UniRef100: UniRef100_Q13029
UniRef90: UniRef90_Q13029
UniRef50: UniRef50_Q13029
UniGene: Hs.371823
CCDS: CCDS44061.1, CCDS150.1, CCDS151.1, CCDS30603.1

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