| Type | Description |
|---|---|
| Definition | retinol dehydrogenase 12 |
| Date | Results | Publications |
|---|---|---|
| 2012-09-29 11:03:00 | RDH12 in inner segments can protect vital cell organelles against aldehyde toxicity caused by an intracellular leak of all-trans-retinal, as well as other aldehydes originating both inside and outside the cell. | 22621924 |
| 2010-01-21 00:00:00 | Oxidative stress induced by exposure to constant bright light led to a rapid and significant decrease of RDH12 protein. The low and constant expression of RDH11 suggested a housekeeping function for this enzyme. | 18326732 |
| 2010-01-21 00:00:00 | The present findings, together with those of earlier studies showing only minor functional deficits in mice deficient for Rdh5, Rdh8, or Rdh11, suggest that the activity of any one isoform is not rate limiting in the visual response. | 17130236 |
| 2010-01-21 00:00:00 | RDH12 plays a unique, nonredundant role in the photoreceptor inner segments to regulate the flow of retinoids in the eye. | 17032653 |
| 2010-01-21 00:00:00 | a critical function of RDH12 is the reduction of all-trans-retinal that exceeds the reductive capacity of the photoreceptor outer segments | 19506076 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RDH12_MOUSE,
A0A0R4J1M3_MOUSE
UniprotKB:
Q8BYK4,
A0A0R4J1M3
UniParc:
UPI0000021B0C,
UPI00000E7C1C
EMBL:
BC016204,
AC154585,
AK039233,
AK020927
Ensembl:
ENSMUSG00000021123
KO:
mmu:77974
|
| Nucleutide sequences |
EMBL-CDS:
BAC30288.1,
BAB32258.1,
AAH16204.1
Ensembl_TRS:
ENSMUST00000021548,
ENSMUST00000122227
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021548,
ENSMUSP00000112543
RefSeq:
NP_001300900.1,
NP_084293.1
|
| Others |
UniRef100:
UniRef100_Q8BYK4,
UniRef100_A0A0R4J1M3
UniRef90:
UniRef90_Q8BYK4
UniRef50:
UniRef50_Q8BYK4
UniGene:
Mm.274373
CCDS:
CCDS26009.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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