| Type | Description |
|---|---|
| Definition | hook microtubule tethering protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-03 11:48:00 | Hook1 is a binding partner of Ccdc181. | 28283191 |
| 2017-05-13 17:24:00 | Single-molecule motility assays using total internal reflection fluorescence microscopy indicate that both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (BICD2). | 27365401 |
| 2010-01-21 00:00:00 | Multiple samples of ejaculated spermatozoa from normal fertile C57BL/6 and infertile Hook1/Hook1 (formerly known as azh/azh) mutant males from uteri after mating. | 17314312 |
| 2010-01-21 00:00:00 | azh mutation is due to a deletion of exons 10 and 11 in the murine Hook1 gene leading to a non-functional protein. Our results indicate that loss of Hook1 function results in ectopic positioning of microtubular structures within the spermatid | 12075009 |
| 2010-01-21 00:00:00 | Hook1 and Ankyrin G are co-locolized, Hook1 also localizes to additional regions of the cell devoid of Ankyrin G where it interacts with other proteins. | 15823567 |
| Type | IDs |
|---|---|
| Synonymous | A930033L17Rik, azh |
| Gene |
UniProtKB-ID:
HOOK1_MOUSE
UniprotKB:
Q8BIL5
UniParc:
UPI0000236D6A,
UPI0000028AE6
EMBL:
AK020924,
BC030877,
BC061688,
AK049897,
AK043870,
AF487912
Ensembl:
ENSMUSG00000028572
KO:
mmu:77963
|
| Nucleutide sequences |
EMBL-CDS:
BAC33977.1,
AAM74055.1,
AAH61688.1,
BAC31686.1,
BAB32257.1,
AAH30877.1
Ensembl_TRS:
ENSMUST00000030306
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030306
RefSeq:
XP_006503551.1,
NP_084290.1,
XP_006503550.1,
XP_030109780.1
|
| Others |
UniRef100:
UniRef100_Q8BIL5
UniRef90:
UniRef90_Q8BIL5
UniRef50:
UniRef50_Q8BIL5
UniGene:
Mm.49994
CCDS:
CCDS18367.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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