Dedicated transcriptomics combined with power analysis lead to functional understanding of genes with weak phenotypic changes in knockout lines.

PLoS Comput Biol     Chen Xie , Cemalettin Bekpen , Sven Künzel , Maryam Keshavarz , Rebecca Krebs-Wheaton , Neva Skrabar , Kristian K Ullrich , Wenyu Zhang , Diethard Tautz

A conditional knockout resource for the genome-wide study of mouse gene function.

Nature     William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.

Genome Res.     Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin

The transcriptional landscape of the mammalian genome.

Science     P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)

Antisense transcription in the mammalian transcriptome.

Science     S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium

Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.

Nat. Methods     Akira Watahiki , Kazunori Waki , Norihito Hayatsu , Toshiyuki Shiraki , Shinji Kondo , Mari Nakamura , Daisuke Sasaki , Takahiro Arakawa , Jun Kawai , Matthias Harbers , Yoshihide Hayashizaki , Piero Carninci

Genomic analysis of mouse retinal development.

PLoS Biol.     Seth Blackshaw , Sanjiv Harpavat , Jeff Trimarchi , Li Cai , Haiyan Huang , Winston P Kuo , Griffin Weber , Kyungjoon Lee , Rebecca E Fraioli , Seo-Hee Cho , Rachel Yung , Elizabeth Asch , Lucila Ohno-Machado , Wing H Wong , Constance L Cepko

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

Nature     Y Okazaki , M Furuno , T Kasukawa , J Adachi , H Bono , S Kondo , I Nikaido , N Osato , R Saito , H Suzuki , I Yamanaka , H Kiyosawa , K Yagi , Y Tomaru , Y Hasegawa , A Nogami , C Schönbach , T Gojobori , R Baldarelli , D P Hill , C Bult , D A Hume , J Quackenbush , L M Schriml , A Kanapin , H Matsuda , S Batalov , K W Beisel , J A Blake , D Bradt , V Brusic , C Chothia , L E Corbani , S Cousins , E Dalla , T A Dragani , C F Fletcher , A Forrest , K S Frazer , T Gaasterland , M Gariboldi , C Gissi , A Godzik , J Gough , S Grimmond , S Gustincich , N Hirokawa , I J Jackson , E D Jarvis , A Kanai , H Kawaji , Y Kawasawa , R M Kedzierski , B L King , A Konagaya , I V Kurochkin , Y Lee , B Lenhard , P A Lyons , D R Maglott , L Maltais , L Marchionni , L McKenzie , H Miki , T Nagashima , K Numata , T Okido , W J Pavan , G Pertea , G Pesole , N Petrovsky , R Pillai , J U Pontius , D Qi , S Ramachandran , T Ravasi , J C Reed , D J Reed , J Reid , B Z Ring , M Ringwald , A Sandelin , C Schneider , C A M Semple , M Setou , K Shimada , R Sultana , Y Takenaka , M S Taylor , R D Teasdale , M Tomita , R Verardo , L Wagner , C Wahlestedt , Y Wang , Y Watanabe , C Wells , L G Wilming , A Wynshaw-Boris , M Yanagisawa , I Yang , L Yang , Z Yuan , M Zavolan , Y Zhu , A Zimmer , P Carninci , N Hayatsu , T Hirozane-Kishikawa , H Konno , M Nakamura , N Sakazume , K Sato , T Shiraki , K Waki , J Kawai , K Aizawa , T Arakawa , S Fukuda , A Hara , W Hashizume , K Imotani , Y Ishii , M Itoh , I Kagawa , A Miyazaki , K Sakai , D Sasaki , K Shibata , A Shinagawa , A Yasunishi , M Yoshino , R Waterston , E S Lander , J Rogers , E Birney , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group Phase I & II Team

Functional annotation of a full-length mouse cDNA collection.

Nature     J Kawai , A Shinagawa , K Shibata , M Yoshino , M Itoh , Y Ishii , T Arakawa , A Hara , Y Fukunishi , H Konno , J Adachi , S Fukuda , K Aizawa , M Izawa , K Nishi , H Kiyosawa , S Kondo , I Yamanaka , T Saito , Y Okazaki , T Gojobori , H Bono , T Kasukawa , R Saito , K Kadota , H Matsuda , M Ashburner , S Batalov , T Casavant , W Fleischmann , T Gaasterland , C Gissi , B King , H Kochiwa , P Kuehl , S Lewis , Y Matsuo , I Nikaido , G Pesole , J Quackenbush , L M Schriml , F Staubli , R Suzuki , M Tomita , L Wagner , T Washio , K Sakai , T Okido , M Furuno , H Aono , R Baldarelli , G Barsh , J Blake , D Boffelli , N Bojunga , P Carninci , M F de Bonaldo , M J Brownstein , C Bult , C Fletcher , M Fujita , M Gariboldi , S Gustincich , D Hill , M Hofmann , D A Hume , M Kamiya , N H Lee , P Lyons , L Marchionni , J Mashima , J Mazzarelli , P Mombaerts , P Nordone , B Ring , M Ringwald , I Rodriguez , N Sakamoto , H Sasaki , K Sato , C Schönbach , T Seya , Y Shibata , K F Storch , H Suzuki , K Toyo-oka , K H Wang , C Weitz , C Whittaker , L Wilming , A Wynshaw-Boris , K Yoshida , Y Hasegawa , H Kawaji , S Kohtsuki , Y Hayashizaki , RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

Genome Res.     K Shibata , M Itoh , K Aizawa , S Nagaoka , N Sasaki , P Carninci , H Konno , J Akiyama , K Nishi , T Kitsunai , H Tashiro , M Itoh , N Sumi , Y Ishii , S Nakamura , M Hazama , T Nishine , A Harada , R Yamamoto , H Matsumoto , S Sakaguchi , T Ikegami , K Kashiwagi , S Fujiwake , K Inoue , Y Togawa