| Type | Description |
|---|---|
| Definition | limb-bud and heart |
| Date | Results | Publications |
|---|---|---|
| 2019-06-08 10:09:00 | LBH plays an essential role in WNT-induced mammary tumorigenesis by promoting hyperplastic growth and tumor formation. | 30509497 |
| 2019-02-02 11:22:00 | These results, obtained from the integrative approach, suggest that LBH and SHF are associated with the Alzheimer's disease pathogenesis. | 30006735 |
| 2017-10-28 13:02:00 | These studies indicate that LBH deficiency induces S-phase arrest that, in turn, exacerbates inflammation. Because LBH gene variants are associated with type I diabetes mellitus, systemic lupus erythematosus, RA, and celiac disease, these results suggest a general mechanism that could contribute to immune-mediated diseases. | 28807995 |
| 2015-04-25 10:25:00 | The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage. | 25655704 |
| 2010-09-20 12:35:00 | LBH is aberrantly overexpressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1-transgenic mice and in aggressive basal subtype human breast cancers that display Wnt/beta-catenin hyperactivation. | 20606007 |
| Type | IDs |
|---|---|
| Synonymous | 1810009F10Rik, 6720416L16Rik |
| Gene |
UniProtKB-ID:
LBH_MOUSE
UniprotKB:
Q9CX60
UniParc:
UPI000002221D
EMBL:
AF317517,
BC052470,
BC026827,
AK020110
Ensembl:
ENSMUSG00000024063
KO:
mmu:77889
|
| Nucleutide sequences |
EMBL-CDS:
BAB31998.1,
AAH26827.1,
AAH52470.1,
AAK38204.1
Ensembl_TRS:
ENSMUST00000024857
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024857
RefSeq:
NP_084275.3
|
| Others |
UniRef100:
UniRef100_Q9CX60
UniRef90:
UniRef90_Q9CX60
UniRef50:
UniRef50_Q9CX60
UniGene:
Mm.154109
CCDS:
CCDS28964.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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