| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase kinase 12 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 13:04:00 | Aryl hydrocarbon receptor enhances the expression of miR-150-5p to suppress cell proliferation and invasion in prostate cancer by regulating MAP3K12 | 30009782 |
| 2017-08-05 10:10:00 | LZK cooperates with DLK to promote retinal ganglion cell death in response to axon injury. | 28641113 |
| 2017-03-25 11:38:00 | REVIEW: Regulation of Beta-Cell Function and Mass by the Dual Leucine Zipper Kinase | 27100796 |
| 2016-02-27 11:40:00 | miR-130a inhibited the JNK pathway by targeting MAP3K12, contributing to its anti-apoptotic effect and the maintenance of diabetic endothelial progenitor cell function. | 25999017 |
| 2015-05-02 12:57:00 | Data suggest that specific pharmacological inhibition of dual leucine zipper kinase (DLK, MAP3K12) may have therapeutic potential in multiple indications of neuronal degeneration. | 25341110 |
| Type | IDs |
|---|---|
| Synonymous | DLK, MEKK12, MUK, ZPK, ZPKP1 |
| Gene |
UniProtKB-ID:
M3K12_HUMAN,
A0A024RAY5_HUMAN
UniprotKB:
Q12852,
A0A024RAY5
UniParc:
UPI00001407EE,
UPI00000730A5
EMBL:
BC050050,
CH471054,
AK094195,
AC023509,
AF283475,
U07358
Ensembl:
ENSG00000139625
KO:
hsa:7786
|
| Nucleutide sequences |
EMBL-CDS:
AAL67158.1,
AAH50050.1,
EAW96715.1,
AAA67343.1,
BAG52841.1,
EAW96712.1,
EAW96713.1
Gene_ORFName:
hCG_23343
Ensembl_TRS:
ENST00000547488,
ENST00000547035,
ENST00000267079
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000267079,
ENSP00000448689,
ENSP00000449038
RefSeq:
XP_005269197.1,
XP_006719651.1,
XP_011537027.1,
XP_005269195.1,
NP_006292.3,
XP_016875445.1,
NP_001180440.1
|
| Others |
UniRef100:
UniRef100_Q12852
UniRef90:
UniRef90_Q12852
UniRef50:
UniRef50_Q60700
UniGene:
Hs.713539
CCDS:
CCDS8860.1,
CCDS55831.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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