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7781 SLC30A3

7781

SLC30A3

solute carrier family 30 member 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 30 member 3

研究结论

Date Results Publications
2018-09-08 10:30:00 ZNT3 was only detected in human beta-cells, but not in mouse beta-cells. 29372370
2017-11-18 12:41:00 SNPs in the SLC30A3 gene and adjacent region are associated with schizophrenia in female but not male cases. 27750116
2017-09-23 12:53:00 There was a significant decreased in protein levels of ZnT3 in the prefrontal cortex in Major depression disorder, relative to control subjects. 27661418
2017-06-03 11:36:00 The level of ERK1/2 phosphorylation was significantly increased by tunicamycin treatment in control cells, not in SLC30A3 knockdown cells. The ERK1/2 pathway is thought to have an association with defensive effects of SLC30A3 on cellular stress such as ER stress. 27678294
2016-12-17 11:48:00 ZNT3 and ZNT8 (known to regulate insulin secretion) have opposite effects on insulin synthesis and secretion possibly by a transcriptional co-regulation since mRNA expression of ZNT3 was inversely correlated to ZNT8 and ZNT3 over-expression reduced insulin synthesis and secretion. 26867900

名称对应

Type IDs
Synonymous ZNT3
Gene
UniProtKB-ID: ZNT3_HUMAN, B4DXX8_HUMAN
UniprotKB: Q99726, B4DXX8
UniParc: UPI00017A801E, UPI000006D0B4
EMBL: AC013413, AK313600, U76010, AK302174, BC028358
Ensembl: ENSG00000115194
KO: hsa:7781
Nucleutide sequences
EMBL-CDS: AAH28358.1, AAY24294.1, AAB39732.1, BAG36366.1, BAG63540.1
Ensembl_TRS: ENST00000233535
Protein sequencees
Ensembl_PRO: ENSP00000233535
RefSeq: XP_011531405.1, NP_001305880.1, XP_016860364.1, NP_001305879.1, XP_005264605.1, XP_016860363.1, XP_016860362.1, NP_001305878.1, XP_011531404.1, NP_003450.2, XP_005264604.1
Others
UniRef100: UniRef100_B4DXX8, UniRef100_Q99726
UniRef90: UniRef90_Q5R617, UniRef90_Q99726
UniRef50: UniRef50_Q5R617, UniRef50_Q99726
UniGene: Hs.467981
CCDS: CCDS1743.1

全选

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