| Type | Description |
|---|---|
| Definition | Src-like-adaptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 11:57:00 | SLAP2 acts as a negative regulator of FLT3 signaling and therefore, modulation of SLAP2 expression levels may provide an alternative therapeutic approach for FLT3-ITD positive acute myeloid leukemia | 27458164 |
| 2015-03-21 10:12:00 | SLAP and SLAP2 are critical inhibitors of platelet (hem)ITAM signaling in the setting of arterial thrombosis and ischemic stroke | 25301707 |
| 2011-04-30 10:42:00 | In bone marrow-derived dendritic cells lacking SLAP and closely related SLAP2, downregulation of the granulocyte-macrophage colony-stimulating factor (GM-CSF)beta receptor is impaired. | 21220694 |
| 2010-01-21 00:00:00 | SLAP-2 plays a role in c-Cbl-dependent down-regulation of CSF-1R signaling | 17353186 |
| Type | IDs |
|---|---|
| Synonymous | A930009E21Rik, AI430952, SLAP-2, SLAP2 |
| Gene |
UniProtKB-ID:
SLAP2_MOUSE
UniprotKB:
Q8R4L0
UniParc:
UPI00003561FD,
UPI000004EC3F
EMBL:
AK030877,
AK088672,
AK020837,
AF287467,
AK138709,
AF434990
Ensembl:
ENSMUSG00000027636
KO:
mmu:77799
|
| Nucleutide sequences |
EMBL-CDS:
AAL38196.1,
BAB32223.1,
BAE23754.1,
BAC40495.1,
AAL86403.1,
BAC27168.1
Ensembl_TRS:
ENSMUST00000109561,
ENSMUST00000029164
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000105189,
ENSMUSP00000029164
RefSeq:
NP_084259.1,
XP_011238148.1,
XP_011238147.1,
NP_001343424.1
|
| Others |
UniRef100:
UniRef100_Q8R4L0
UniRef90:
UniRef90_Q8R4L0
UniRef50:
UniRef50_Q9H6Q3
UniGene:
Mm.29264,
Mm.387161
CCDS:
CCDS38302.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 27458164 |
Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling. Oncotarget Sausan A Moharram , Rohit A Chougule , Xianwei Su , Tianfeng Li , Jianmin Sun , Hui Zhao , Lars Rönnstrand , Julhash U Kazi |
2016-09-06 | - |
| 25301707 |
SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice. Blood Deya Cherpokova , Markus Bender , Martina Morowski , Peter Kraft , Michael K Schuhmann , Sarah M Akbar , Cheryl S Sultan , Craig E Hughes , Christoph Kleinschnitz , Guido Stoll , Leonard L Dragone , Steve P Watson , Michael G Tomlinson , Bernhard Nieswandt |
2015-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21220694 |
The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation. J. Immunol. Larissa M Liontos , Dilan Dissanayake , Pamela S Ohashi , Arthur Weiss , Leonard L Dragone , C Jane McGlade |
2011-02-15 |
Sla,
Sla2
|
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 17353186 |
J Biol Chem Benjamin Pakuts , Christophe Debonneville , Larissa M Liontos , Michael P Loreto , C Jane McGlade |
2007-06-22 | - |
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 15782199 |
Nat. Methods Akira Watahiki , Kazunori Waki , Norihito Hayatsu , Toshiyuki Shiraki , Shinji Kondo , Mari Nakamura , Daisuke Sasaki , Takahiro Arakawa , Jun Kawai , Matthias Harbers , Yoshihide Hayashizaki , Piero Carninci |
2004-12-01 |
Ldlrap1,
Mfap1b,
Dnajc3,
Fam129c,
Rsph3b,
Rnaset2a,
Fam174b,
Gm9797,
Gm2296,
Gm15429,
Atp6v0c-ps2,
Kcnj13,
Gm10291,
Gm15264,
Rpl3-ps1,
Gm4482,
Srcap,
Tpt1-ps3,
Rps2-ps6,
Orai2-ps,
Tdrd7,
Sco2,
Pafah2,
Akna,
H6pd,
Stx12,
Gm15590,
Osbpl9,
AU040320,
Ppp1r8,
Bsdc1,
Gm37013,
Slc44a1,
Zfand2a,
Rpl5,
LOC100503956,
Atg14,
Rell1,
Slc15a4,
Noc4l,
Psph,
9330133O14Rik,
Mapre3,
Usp30,
Ube3c,
Rita1,
Tbc1d14,
Gm21685,
Chpf2,
Tyw1,
Rab28,
Zfp513,
LOC101055802,
Zfp282,
Snx21,
Rpusd3,
Itfg2,
Pot1a,
Tada3,
Brk1,
Eogt,
Dhx32,
Ric8a,
Inpp5f,
Plekhg2,
Hsd3b7,
Mob2,
Prkd2,
Vrk3,
Grwd1,
Pwwp2b,
Spty2d1,
Faap24,
Ints4,
Rrp8,
Unc45a,
Sf3b3,
D8Ertd738e,
Usb1,
Smim19,
Dohh,
Fam192a,
Enkd1,
Prmt9,
Zdhhc7,
Snapc2,
Gpat4,
Ankrd10,
Cog4,
Clk3,
Xylb,
Imp3,
Cmtm7,
Ano10,
Alg9,
Plekho2,
Mapkapk3,
Acad11,
Gm30491
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员