tpcn2 - two pore segment channel 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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777614 tpcn2

基因描述

Type	Description
Definition	two pore segment channel 2

研究结论

Date	Results	Publications
2018-06-02 12:06:00	Data suggest a novel function for NAADP/TPC2-mediated Ca(2+) signaling in the development, coordination, and maturation of the spinal network in zebrafish embryos.	29577882
2017-09-16 11:02:00	localized calcium (Ca(2+)) release via TPC2 might trigger the generation of more global Ca(2+) release from the sarcoplasmic reticulum via Ca(2+)-induced Ca(2+) release.	28390800
2016-10-08 11:54:00	TPC2-mediated Ca(2+) release from lysosomes may act upstream from RyR- and IP 3R-mediated Ca(2+) release, suggesting that the former might initiate the SR-mediated Ca(2+)-induced-Ca(2+)-release essential for SMC myogenesis and function.	26679948

名称对应

Type	IDs
Synonymous	fi42c05, im:7140344, wu:fi42c05, zgc:152898
Gene	UniProtKB-ID: TPC2_DANRE UniprotKB: A0JMD4 UniParc: UPI0000E6734C EMBL: BC125833 KO: dre:777614
Nucleutide sequences	EMBL-CDS: AAI25834.1 Gene_ORFName: zgc:152898
Protein sequencees	RefSeq: NP_001071190.1
Others	UniRef100: UniRef100_A0JMD4 UniRef90: UniRef90_A0JMD4 UniRef50: UniRef50_A0JMD4 UniGene: Dr.133033, Dr.156799

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29577882	TPC2-mediated Ca²⁺ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons. Dev. Biol. Jeffrey J Kelu , Sarah E Webb , Antony Galione , Andrew L Miller	2018-06-01	-
28390800	Ca²⁺ release via two-pore channel type 2 (TPC2) is required for slow muscle cell myofibrillogenesis and myotomal patterning in intact zebrafish embryos. Dev. Biol. Jeffrey J Kelu , Sarah E Webb , John Parrington , Antony Galione , Andrew L Miller	2017-05-15	-
27189481	Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. BMC Genomics Jeremy Pasquier , CÃ©dric Cabau , Thaovi Nguyen , Elodie Jouanno , Dany Severac , Ingo Braasch , Laurent Journot , Pierre Pontarotti , Christophe Klopp , John H Postlethwait , Yann Guiguen , Julien Bobe	2016-05-18	-
25650066	Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria. J. Med. Genet. JosÃ©-Mario Capo-Chichi , Sarah Boissel , Edna Brustein , Sarah Pickles , Catherine Fallet-Bianco , Christina Nassif , Lysanne Patry , Sylvia Dobrzeniecka , Meijiang Liao , Damian Labuda , Mark E Samuels , Fadi F Hamdan , Christine Vande Velde , Guy A Rouleau , Pierre Drapeau , Jacques L Michaud	2015-05-01	madd, myo7aa, tpcn2, CLPB
26679948	Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca(2+) signaling during myogenesis in intact zebrafish. Int. J. Dev. Biol. Jeffrey J Kelu , Hayley L H Chan , Sarah E Webb , Arthur H H Cheng , Margarida Ruas , John Parrington , Antony Galione , Andrew L Miller	2015-01-01	-
25256615	A non-inactivating high-voltage-activated two-pore Naâº channel that supports ultra-long action potentials and membrane bistability. Nat Commun Chunlei Cang , Kimberly Aranda , Dejian Ren	2014-09-26	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-

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