| Type | Description |
|---|---|
| Definition | zinc finger protein 224 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-01 10:04:00 | identify the receptor tyrosine kinase Axl as a novel target of ZNF224 transcriptional repression activity. | 30176265 |
| 2018-01-20 10:43:00 | The analyses using human breast ductal carcinoma tissues exhibited that the expression of ZNF224 and miR-663a was increased in cancer compared to non-cancer region. | 27105517 |
| 2017-09-23 10:45:00 | we showed that ZNF224 positively modulates cyclin D3 gene expression. Consistently, we observed that alteration of ZNF224 expression leads to defects in cell cycle control. All together, our results strongly suggest that in Chronic lymphocytic leukaemia (CLL)cells high expression level of ZNF224 can lead to inappropriate cell growth and apoptosis resistance, thus contributing to CLL progression | 28040726 |
| 2017-06-24 10:12:00 | Increasing information on the mechanism through which ZNF224 can operate could lead to the identification of agents capable of modulating ZNF224 function, thus potentially paving the way to new therapeutic strategies for treatment of cancer | 28215224 |
| 2016-08-06 10:06:00 | Data show that Wilms' tumor 1 protein (WT1)binds to the zinc finger protein 224 (ZNF224) promoter and represses ZNF224 expression. | 26320177 |
| Type | IDs |
|---|---|
| Synonymous | BMZF-2, BMZF2, KOX22, ZNF233, ZNF255, ZNF27 |
| Gene |
UniProtKB-ID:
ZN224_HUMAN
UniprotKB:
Q9NZL3
UniParc:
UPI00002025B3
EMBL:
AF187990,
AC021092,
AC084219,
AC114266,
AY148489,
X52353,
AF067164,
BC051902
Ensembl:
ENSG00000267680
KO:
hsa:7767
|
| Nucleutide sequences |
EMBL-CDS:
AAF24968.1,
AAH51902.1,
AAN61121.1,
AAF04106.2,
CAA36579.1,
AAD32448.1
Ensembl_TRS:
ENST00000336976
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000337368
RefSeq:
XP_016882750.1,
NP_037530.2,
NP_001308574.1
|
| Others |
UniRef100:
UniRef100_Q9NZL3
UniRef90:
UniRef90_Q9NZL3
UniRef50:
UniRef50_Q9NZL3
UniGene:
Hs.585869,
Hs.744152
CCDS:
CCDS33046.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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