| Type | Description |
|---|---|
| Definition | apurinic/apyrimidinic endonuclease 2 |
| Date | Results | Publications |
|---|---|---|
| 2015-05-16 10:33:00 | expression of Apex 2 in chondrocytes appears to be associated with the degeneration of articular cartilage in osteoarthritis. | 25158232 |
| 2014-10-04 10:58:00 | Results indicate a role for apurinic/apyrimidinic endonuclease (APE) 2 (Apex2) in the protection of germinal center (GC) cells from activation-induced cytidine deaminase (AID)-independent damage. | 24935922 |
| 2014-08-23 10:53:00 | data provide new insight into error-prone repair of AID-induced lesions, which we propose is facilitated by down-regulation of APE1 and up-regulation of APE2 expression in germinal center B cells. | 24927551 |
| 2011-04-30 10:35:00 | Extensive analysis of bone marrow hematopoiesis in APE2-deficient mice finds inhibition of the pro-B to pre-B lymphocyte transition, due to a p53-dependent DNA damage response, independent from its ubiquitous and essential homolog APE1. | 21228350 |
| 2010-01-21 00:00:00 | The present study clearly demonstrates that APEX2-null lymphocytes have a higher frequency of DNA breaks, indicating that APEX2 may play an important role(s) during their generation and/or repair. | 18585982 |
| Type | IDs |
|---|---|
| Synonymous | C430040P13Rik, ape2 |
| Gene |
UniProtKB-ID:
APEX2_MOUSE,
A2AFM3_MOUSE
UniprotKB:
Q68G58,
A2AFM3
UniParc:
UPI0000027B1D,
UPI00000EA999,
UPI00000EA55F,
UPI0000028121,
UPI0000419E4E,
UPI000058E4B1
EMBL:
AK088918,
BC078633,
AK040145,
AB072498,
AL808140,
AK080916,
AK021248,
AK050858,
AL672150,
AK081677,
BC026769,
AB085235
Ensembl:
ENSMUSG00000025269
KO:
mmu:77622
|
| Nucleutide sequences |
EMBL-CDS:
BAC11807.1,
BAB32346.1,
AAH78633.1,
BAC34436.1,
AAH26769.1,
BAC40652.1,
BAB88654.1,
BAC38287.1,
BAC30522.1,
BAC38077.1
Ensembl_TRS:
ENSMUST00000112727,
ENSMUST00000112725,
ENSMUST00000026303,
ENSMUST00000112720
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108345,
ENSMUSP00000108347,
ENSMUSP00000026303,
ENSMUSP00000108340
RefSeq:
XP_011246181.1,
XP_036018009.1,
XP_030107378.1,
NP_084219.1,
XP_036018008.1,
XP_006529054.1
|
| Others |
UniRef100:
UniRef100_A2AFM3,
UniRef100_Q68G58
UniRef90:
UniRef90_Q68G58
UniRef50:
UniRef50_Q9UBZ4
UniGene:
Mm.440275
CCDS:
CCDS30463.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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