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7756 ZNF207

7756

ZNF207

zinc finger protein 207

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger protein 207

研究结论

Date Results Publications
2021-03-13 13:17:00 BuGZ facilitates loading of spindle assembly checkpoint proteins to kinetochores in early mitosis. 32820050
2019-06-01 10:07:00 ZNF207 expression is elevated in hepatocellular carcinoma 31113916
2019-01-05 12:08:00 a distinct isoform of ZNF207 functions in hESCs at the nexus that balances pluripotency and differentiation to ectoderm. 30349051
2018-11-03 11:17:00 the two zinc fingers of BuGZ directly bind to AurA and BuGZ coacervation appears to promote AurA activation during spindle assembly. 29074706
2015-12-26 11:49:00 BuGZ forms temperature-dependent liquid droplets alone or on microtubules in physiological buffers. Coacervation in vitro or in spindle and spindle matrix depends on hydrophobic residues in BuGZ. BuGZ coacervation and its binding to microtubules and tubulin are required to promote assembly of spindle and spindle matrix in Xenopus egg extract and in mammalian cells. 26388440

名称对应

Type IDs
Synonymous BuGZ, hBuGZ
Gene
UniProtKB-ID: ZN207_HUMAN
UniprotKB: O43670
UniParc: UPI000002B72A, UPI000002B72B, UPI000013C31B, UPI000020164D
EMBL: AK291801, BC002372, BC008023, AK226172, CH471147, BT007365, AC005899, AF046001
Ensembl: ENSG00000010244
KO: hsa:7756
Nucleutide sequences
EMBL-CDS: BAF84490.1, AAP36029.1, AAH08023.1, EAW80231.1, EAW80233.1, AAH02372.1, EAW80236.1, EAW80235.1, EAW80237.1, AAC78561.1, EAW80234.1
Ensembl_TRS: ENST00000394670, ENST00000321233, ENST00000394673
Protein sequencees
Ensembl_PRO: ENSP00000378168, ENSP00000322777, ENSP00000378165
RefSeq: NP_001091977.1, NP_003448.1, NP_001027464.1
Others
UniRef100: UniRef100_O43670
UniRef90: UniRef90_O43670
UniRef50: UniRef50_O43670
UniGene: Hs.500775
CCDS: CCDS11271.1, CCDS42294.1, CCDS32614.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

University of Toronto

6
2

Carnegie Institution for Science

4
3

Institute of Biochemistry and Cell Biology

4
4

Beijing Institute of Radiation Medicine

3
5

Max Planck Institute of Molecular Cell Biology and Genetics

2
热点人员
排名 研究人员 文献
1

Yixian Zheng

4
2

Xueliang Zhu

4
3

Steven P Gygi

3
4

J Wade Harper

3
5

Andrew Emili

3
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