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7750 ZMYM2

7750

ZMYM2

zinc finger MYM-type containing 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger MYM-type containing 2

研究结论

Date Results Publications
2021-01-16 15:54:00 Characterization of the zinc finger proteins ZMYM2 and ZMYM4 as novel B-MYB binding proteins. 32439918
2020-12-05 13:01:00 Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations. 32891193
2019-09-07 10:58:00 study found that ZMYM2-FLT3 and DIAPH1-PDGFRB fusion genes are novel, cytogenetically cryptic and therapeutically targetable abnormalities in myeloproliferative neoplasms with eosinophilia, and are thus reminiscent of FIP1L1-PDGFRA positive myeloid neoplasms 28751768
2017-04-29 10:51:00 In this report we described the first successful development of a model of human ZMYM2-FGFR1 driven AML in immunocompromised mice, which shows an etiology consistent with the development of the primary human disease. 27005999
2016-01-16 11:36:00 Multi-SUMO binding is mediated through multi-SIM modules, and the functional importance of these interactions is demonstrated for the transcriptional corepressor ZMYM2/ZNF198 26283374

名称对应

Type IDs
Synonymous FIM, MYM, RAMP, SCLL, ZNF198
Gene
UniProtKB-ID: ZMYM2_HUMAN, A0A024RDS3_HUMAN, A8K126_HUMAN
UniprotKB: Q9UBW7, A0A024RDS3, A8K126
UniParc: UPI00001AE7FC, UPI000013C318, UPI00015DA602
EMBL: BX647944, AJ007681, Y13472, AJ007695, AF060181, AJ007679, AJ007690, CH471075, AJ007682, AJ007693, AJ007684, AJ224901, AK289741, AJ007678, AJ007687, AJ007676, AL136621, AJ007683, AJ007677, AJ007688, BC036372, AJ007696, AF035374, AL138688, AJ007694, AJ007680, AJ007685, AJ007692, AL137119, AJ007689, AJ007691, AF012126, AJ007686
Ensembl: ENSG00000121741
KO: hsa:7750
Nucleutide sequences
EMBL-CDS: CAH56193.1, CAA12204.1, CAB66556.2, AAB88464.1, CAA73875.1, AAC01561.1, EAX08247.1, EAX08244.1, AAH36372.1, AAC23591.1, CAA07604.1, EAX08245.1, EAX08248.1, EAX08246.1, BAF82430.1
Gene_ORFName: hCG_20496
Ensembl_TRS: ENST00000382871, ENST00000382874, ENST00000610343
Protein sequencees
Ensembl_PRO: ENSP00000479904, ENSP00000372324, ENSP00000372327
RefSeq: XP_024305176.1, XP_005266577.1, XP_011533524.1, NP_001340093.1, XP_016876224.1, XP_016876223.1, XP_016876226.1, NP_001340086.1, NP_001340094.1, XP_016876221.1, NP_001340090.1, NP_001340088.1, XP_016876220.1, NP_001340092.1, XP_011533525.1, NP_932072.1, XP_016876222.1, NP_001340091.1, NP_003444.1, NP_001177894.1, XP_024305175.1, XP_024305174.1, NP_001177893.1
Others
UniRef100: UniRef100_A8K126, UniRef100_Q9UBW7
UniRef90: UniRef90_Q5RDJ2, UniRef90_Q9UBW7
UniRef50: UniRef50_Q9UBW7
UniGene: Hs.507433
CCDS: CCDS45016.1

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